Behymer D E, Biberstein E L, Riemann H P, Franti C E, Sawyer M
Am J Vet Res. 1975 Jun;36(6):781-84.
The immune response and persistence of antibodies were investigated in dairy cattle vaccinated with formalin-inactivated phase (ph) I Coxiella burnetii vaccine agglutinating antibody geometric mean titer (GMT) of 193.2 at 1 month after vaccination compared to a GMT of 2.0 for nonvaccinated calves. The agglutinating antibodies gradually decreased in vaccinated cattle, but the GMT remained approximately 4 times higher than that for the nonvaccinated group for at least 20 months. Results of serotests at 2 months after revaccination indicated a rapid increase in the GMT to 177.0 with agglutinating titers between 1:64 and 1:512.
对用福尔马林灭活的Ⅰ期伯氏考克斯氏体疫苗接种的奶牛的免疫反应和抗体持久性进行了研究。接种疫苗后1个月，凝集抗体几何平均滴度（GMT）为193.2，而未接种疫苗的犊牛的GMT为2.0。接种疫苗的牛体内凝集抗体逐渐下降，但至少20个月内，其GMT仍比未接种组高约4倍。再次接种疫苗2个月后的血清学检测结果表明，GMT迅速升至177.0，凝集滴度在1:64至1:512之间。
