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透明质酸填充剂注射血管并发症的管理策略:病例系列分析

Management strategies for vascular complications in hyaluronic acid filler injections: A case series analysis.

作者信息

Choi Sun Young, Shin Sun Hye, Seok Joon, Yoo Kwang Ho, Kim Beom Joon

机构信息

Department of Dermatology, Chung-Ang University Gwangmyeong Hospital, Chung-Ang University College of Medicine, Gwangmyeong-si, Republic of Korea.

Department of Dermatology, Chung-Ang University College of Medicine, Seoul, Republic of Korea.

出版信息

J Cosmet Dermatol. 2023 Dec;22(12):3261-3267. doi: 10.1111/jocd.15990. Epub 2023 Sep 11.

Abstract

BACKGROUND

As hyaluronic acid (HA) filler injections have become increasingly popular in the esthetic field, so have their side effects. Vascular complications, which can lead to skin necrosis or permanent scarring, are a particularly dangerous complication and occur when the filler is injected directly into a blood vessel or when an adjacent blood vessel is compressed by the filler material.

OBJECTIVE

To assess the clinical prognosis based on post-procedural management and clinical findings of HA filler vascular complications.

METHODS

Herein, we present a case series of vascular complications due to HA filler and evaluate their clinical prognosis based on post-procedural management and clinical findings. Clinical assessments were performed using Doppler ultrasound, thermography, and laboratory tests.

RESULTS

Factors including white blood cell count, the time of treatment initiation, and time of hyaluronidase injection influenced the clinical outcomes. Early recognition and prompt hyaluronidase injection proved crucial in preventing further damage and improving prognosis.

CONCLUSION

This case series highlights the importance of early detection and appropriate management of HA filler complications. Physicians should be aware of the potential risks associated with fillers and promptly address any adverse effects to achieve optimal clinical outcomes. Further studies are warranted to confirm these findings and refine treatment strategies for the HA filler complications.

摘要

背景

随着透明质酸(HA)填充剂注射在美容领域越来越受欢迎,其副作用也日益增多。血管并发症是一种特别危险的并发症,可导致皮肤坏死或永久性瘢痕形成,当填充剂直接注入血管或相邻血管被填充材料压迫时就会发生。

目的

根据HA填充剂血管并发症的术后管理和临床发现评估临床预后。

方法

在此,我们呈现一组HA填充剂所致血管并发症的病例系列,并根据术后管理和临床发现评估其临床预后。使用多普勒超声、热成像和实验室检查进行临床评估。

结果

包括白细胞计数、开始治疗时间和注射透明质酸酶时间等因素影响临床结果。早期识别并及时注射透明质酸酶对于防止进一步损伤和改善预后至关重要。

结论

该病例系列突出了早期发现和适当处理HA填充剂并发症的重要性。医生应意识到与填充剂相关的潜在风险,并及时处理任何不良反应以实现最佳临床结果。有必要进行进一步研究以证实这些发现并完善HA填充剂并发症的治疗策略。

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