Meyerson B J
Med Biol. 1979 Apr;57(2):69-83.
In recent years evidence has accumulated that hypothalamic hormones may influence behaviour directly, independently of their hypophysiotropic effects. Such a dual role has also been shown for several peptide hormones of pituitary and peripheral origin. The present synopsis is concerned with the effects of neuropeptides on spontaneous behaviour, acquired responses in certain psychological test situations, and drug-induced behavioural effects. A growing body of evidence suggests, that neuropeptides are involved in different behavioural processes. Some peptides selectively influence behaviours such as feeding, drinking, sexual responses etc. Other neuropeptides seem to influence behaviour by acting on processes which are a common integral part of the production of behaviour, namely the ability to receive environmental stimuli, to consolidate, retain and retrieve information. The insight into these mechanisms is important for the understanding of mental disturbances and in order to find specific therapy.
近年来，越来越多的证据表明，下丘脑激素可能直接影响行为，而与其促垂体作用无关。垂体和外周来源的几种肽类激素也显示出这种双重作用。本综述关注神经肽对自发行为、在某些心理测试情境中的习得反应以及药物诱导的行为效应的影响。越来越多的证据表明，神经肽参与了不同的行为过程。一些肽选择性地影响诸如进食、饮水、性反应等行为。其他神经肽似乎通过作用于行为产生过程中一个共同的组成部分，即接收环境刺激、巩固、保留和检索信息的能力，来影响行为。深入了解这些机制对于理解精神障碍以及寻找特定治疗方法很重要。
