Department of Biology, Faculty of Science, Chulalongkorn University, Bangkok, 10330, Thailand.
Center of Excellence in Systems Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330, Thailand.
Sci Rep. 2023 Sep 11;13(1):14950. doi: 10.1038/s41598-023-42220-z.
The environment has an important effect on the gut microbiota-an essential part of the host's health-and is strongly influenced by the dietary pattern of the host as these together shape the composition and functionality of the gut microbiota in humans and other animals. This study compared the gut microbiota of Macaca fascicularis fascicularis and M. f. aurea in mangrove and island populations using 16S rRNA gene sequencing on a nanopore platform to investigate the effect of the environment and/or diet. The results revealed that the M. f. fascicularis populations that received anthropogenic food exhibited a higher richness and evenness of gut microbiota than the M. f. aurea populations in different habitats. Firmicutes and Bacteroidetes were the two most abundant bacterial phyla in the gut microbiota of both these subspecies; however, the relative abundance of these phyla was significantly higher in M. f. aurea than in M. f. fascicularis. This variation in the gut microbiota between the two subspecies in different habitats mostly resulted from the differences in their diets. Moreover, the specific adaptation of M. f. aurea to different environments with a different food availability had a significant effect on their microbial composition.
环境对肠道微生物群有重要影响，而肠道微生物群是宿主健康的重要组成部分，并且强烈受到宿主饮食模式的影响，因为这些因素共同塑造了人类和其他动物肠道微生物群的组成和功能。本研究使用纳米孔平台上的 16S rRNA 基因测序，比较了红树林和岛屿种群中食蟹猴（Macaca fascicularis fascicularis）和金黄猕猴（M. f. aurea）的肠道微生物群，以调查环境和/或饮食的影响。结果表明，接受人为食物的食蟹猴种群的肠道微生物群丰富度和均匀度均高于不同生境中的金黄猕猴种群。厚壁菌门和拟杆菌门是这两个亚种肠道微生物群中最丰富的两个细菌门；然而，这些门的相对丰度在金黄猕猴中明显高于食蟹猴。这两个亚种在不同生境中的肠道微生物群之间的这种差异主要是由于它们饮食的差异。此外，金黄猕猴对不同食物可利用性的不同环境的特定适应对其微生物组成有显著影响。
