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Rathke 裂隙囊肿合并破裂前交通动脉瘤:病例报告。

Rathke's cleft cyst discovered with ruptured anterior communicating artery aneurysm: a case report.

机构信息

Department of Clinical Sciences, Faculty of Medicine, General Sir John Kotelawala Defence University, Ratmalana, Sri Lanka.

Diabetes and Endocrine Unit, National Hospital of Sri Lanka, Colombo 10, Sri Lanka.

出版信息

J Med Case Rep. 2023 Sep 12;17(1):388. doi: 10.1186/s13256-023-04115-5.

Abstract

INTRODUCTION

Rathke's cleft cysts are thought to have a benign clinical outcome apart from associated hypopituitarism and visual defects. Synchronous central nervous system lesions, including pituitary adenoma and intracerebral aneurysms, are rarely reported. Diagnosis of Rathke's cleft cyst after presenting with a subarachnoid hemorrhage due to a ruptured arterial aneurysm is reported only once before.

CASE PRESENTATION

A 33-year-old Sri Lankan female presented with a subarachnoid hemorrhage due to a ruptured anterior communication artery aneurysm. She underwent pterional craniotomy and aneurysm clipping. She was found to have partial cranial diabetes insipidus and hypogonadotropic hypogonadism. She had a cystic lesion occupying enlarged sella turcica with characteristics of a Rathke's cleft cyst. Subsequently, she underwent trans-sphenoidal excision of the sellar lesion. Histology confirmed the diagnosis of Rathke's cleft cyst.

CONCLUSIONS

Rare co-occurrence of a Rathke's cleft cyst and an anterior communicating artery aneurysm would have been missed if subtle manifestations atypical for subarachnoid hemorrhage were not further pursued. This could have led to progressive visual deterioration and hypopituitarism.

摘要

简介

Rathke 氏裂囊肿除了与垂体功能减退和视力缺陷有关外,其临床表现通常为良性。同时发生的中枢神经系统病变,包括垂体腺瘤和颅内动脉瘤,很少有报道。由于动脉性动脉瘤破裂导致蛛网膜下腔出血而诊断为 Rathke 氏裂囊肿的病例以前仅报告过一例。

病例介绍

一位 33 岁的斯里兰卡女性因前交通动脉动脉瘤破裂导致蛛网膜下腔出血而就诊。她接受了翼点开颅术和动脉瘤夹闭术。发现她患有部分性颅神经垂体性尿崩症和促性腺激素低下性性腺功能减退症。她的蝶鞍扩大,有囊性病变,具有 Rathke 氏裂囊肿的特征。随后,她接受了经蝶窦切除鞍区病变。组织学证实了 Rathke 氏裂囊肿的诊断。

结论

如果不进一步探讨蛛网膜下腔出血不典型的细微表现,Rathke 氏裂囊肿和前交通动脉动脉瘤的罕见同时发生可能会被遗漏。这可能导致视力进行性恶化和垂体功能减退。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd71/10496158/7c56a972f217/13256_2023_4115_Fig1_HTML.jpg

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