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由拉克氏裂囊肿破裂引起的伴有全垂体功能减退的短暂甲状腺毒症。

Transient thyrotoxicosis accompanied by panhypopituitarism caused by ruptured Rathke's cleft cyst.

作者信息

Chung Jin Ook, Cho Dong Hyeok, Chung Dong Jin, Chung Min Young

机构信息

Division of Endocrinology and Metabolism, Department of Internal Medicine, Chonnam National University Medical School, Republic of Korea.

出版信息

Intern Med. 2011;50(24):2997-3001. doi: 10.2169/internalmedicine.50.5693. Epub 2011 Dec 15.

DOI:10.2169/internalmedicine.50.5693
PMID:22185992
Abstract

We describe a rare case of transient thyrotoxicosis secondary to painless thyroiditis accompanied by panhypopituitarism caused by ruptured Rathke's cleft cyst. A 32-year-old man presented with vomiting and diarrhea. Laboratory data showed that he had transient hypercalcemia, primary thyrotoxicosis due to painless thyroiditis and panhypopituitarism. The sellar magnetic resonance imaging showed cystic macroadenoma. He underwent surgical exploration. Histological examination showed a ruptured Rathke's cleft cyst. Our case suggests that, although rare, it is important to recognize the possibility of coexistence of hypopituitarism in patients with primary thyrotoxicosis.

摘要

我们描述了一例罕见的继发于无痛性甲状腺炎的短暂性甲状腺毒症病例,该病例伴有因拉克氏裂囊肿破裂导致的全垂体功能减退。一名32岁男性出现呕吐和腹泻症状。实验室检查数据显示他患有短暂性高钙血症、无痛性甲状腺炎所致的原发性甲状腺毒症以及全垂体功能减退。蝶鞍磁共振成像显示为囊性大腺瘤。他接受了手术探查。组织学检查显示拉克氏裂囊肿破裂。我们的病例表明,虽然罕见,但认识到原发性甲状腺毒症患者中存在垂体功能减退共存的可能性很重要。

相似文献

1
Transient thyrotoxicosis accompanied by panhypopituitarism caused by ruptured Rathke's cleft cyst.由拉克氏裂囊肿破裂引起的伴有全垂体功能减退的短暂甲状腺毒症。
Intern Med. 2011;50(24):2997-3001. doi: 10.2169/internalmedicine.50.5693. Epub 2011 Dec 15.
2
Panhypopituitarism due to pituitary cyst of Rathke's cleft origin--two case reports.源于拉克氏裂囊肿的全垂体功能减退症——两例病例报告
Ann Acad Med Singap. 2001 Nov;30(6):651-5.
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Rathke's cleft cyst discovered with ruptured anterior communicating artery aneurysm: a case report.Rathke 裂隙囊肿合并破裂前交通动脉瘤:病例报告。
J Med Case Rep. 2023 Sep 12;17(1):388. doi: 10.1186/s13256-023-04115-5.
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[A case of Rathke's cleft cyst in association with a ruptured aneurysm of the anterior cerebral artery mimicking pituitary apoplexy].[1例拉克氏裂囊肿合并大脑前动脉破裂性动脉瘤,酷似垂体卒中]
No Shinkei Geka. 2002 Feb;30(2):199-203.
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Intraparenchymal infiltration of Rathke's cleft cysts manifesting as severe neurological deficits and hypopituitarism: 2 case reports.表现为严重神经功能缺损和垂体功能减退的Rathke裂囊肿实质内浸润:2例报告
BMC Res Notes. 2016 Apr 19;9:225. doi: 10.1186/s13104-016-2035-1.
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Intra-sellar salivary gland-like pleomorphic adenoma arising within the wall of a Rathke's cleft cyst.起源于拉克氏裂囊肿壁内的鞍内涎腺样多形性腺瘤。
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[Secondary pan-hypophysitis caused by rupture of Rathke's cleft cyst: case report].[拉克氏裂囊肿破裂导致的继发性全垂体炎:病例报告]
No Shinkei Geka. 2002 Jan;30(1):95-9.
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Rathke's cleft cyst rupture as potential initial event of a secondary perifocal lymphocytic hypophysitis: proposal of an unusual pathogenetic event and review of the literature.拉克氏裂囊肿破裂作为继发性灶周淋巴细胞性垂体炎的潜在初始事件:一种不寻常发病机制事件的提议及文献综述
Neurosurg Rev. 2008 Apr;31(2):157-63. doi: 10.1007/s10143-008-0120-1. Epub 2008 Feb 6.

引用本文的文献

1
Rathke cleft cyst masquerading as pituitary abscess: A case report.伪装成垂体脓肿的拉克氏裂囊肿:一例报告。
Medicine (Baltimore). 2017 Mar;96(10):e6303. doi: 10.1097/MD.0000000000006303.
2
Life-Threatening Hypercalcemia due to Graves' Disease and Concomitant Adrenal Failure: A Case Report and Review of the Literature.格雷夫斯病伴发肾上腺功能衰竭所致危及生命的高钙血症:一例报告并文献复习
Case Rep Endocrinol. 2015;2015:684648. doi: 10.1155/2015/684648. Epub 2015 Mar 24.