Hu W H
Zhonghua Zhong Liu Za Zhi. 1986 Mar;8(2):133-5.
Dermatomyositis with malignant tumor is rare in China. The incidence reported abroad was about 7-34%. Before 1982, only 51 cases were collected from the Chinese medical literatures comprising 20.3% (51/251) of patients with dermatomyositis. In 40 (78%) out of 51 patients with co-existing dermatomyositis and malignant tumors, it was NPC. During the period of 1964-1982, in Zhongshan Medical College Tumor Hospital, 30 cases (0.023%) of dermatomyositis complicated with NPC were collected from 127,900 cancer patients. In the 30 cases, 21 (70%) were over the age of 40. In Guangdong province, dermatomyositis with NPC was most frequent in cases of dermatomyositis with malignant tumor (40/44, 91%). The symptom of dermatomyositis occurred prior to that of NPC by eight months. Its disappearance was positively correlated to that of the tumor. The downward invasion of lymph nodes was dominant in dermatomyositis with NPC (28/30, 93.4%). The 5 year survival rate of dermatomyositis with NPC treated by radiation was 16.7% (4/24) which was lower than that of patients without dermatomyositis in the same period.
伴发恶性肿瘤的皮肌炎在中国较为罕见。国外报道的发病率约为7% - 34%。1982年以前，从中国医学文献中仅收集到51例，占皮肌炎患者的20.3%（51/251）。在51例同时患有皮肌炎和恶性肿瘤的患者中，40例（78%）为鼻咽癌。1964 - 1982年期间，中山医学院肿瘤医院从127,900例癌症患者中收集到30例（0.023%）皮肌炎合并鼻咽癌的病例。在这30例中，21例（70%）年龄超过40岁。在广东省，皮肌炎合并鼻咽癌在伴发恶性肿瘤的皮肌炎病例中最为常见（40/44，91%）。皮肌炎症状先于鼻咽癌症状出现8个月。其消失与肿瘤的消失呈正相关。皮肌炎合并鼻咽癌时，淋巴结向下侵犯较为常见（28/30，93.4%）。接受放疗的皮肌炎合并鼻咽癌患者的5年生存率为16.7%（4/24），低于同期无皮肌炎的患者。
