Hu W J, Chen D L, Min H Q
Department of Radiotherapy, Sun Yat-sen University of Medical Sciences, Guangzhou, Peoples Republic of China.
Am J Clin Oncol. 1996 Feb;19(1):35-8. doi: 10.1097/00000421-199602000-00008.
The authors have conducted a study of 61 cases of nasopharyngeal carcinoma (NPC) with dermatomyositis (DM) admitted to the hospital between April 1964 and May 1989 and accounting for 0.027% (61/226, 183) of all the malignant tumors at the hospital and 0.086% (61/70,899) of the nasopharyngeal carcinoma cases, during that time period. We have analyzed 45 cases with complete data, using equal number of age-, sex-, and stage-matched cases with only NPC as control. The findings show a 5- and 10-year survival rate and distant metastatic rate of 50.4, 34.5, and 40.5% respectively, for NPC with DM, and 57.8, 55.2, and 56.5% for controls. The results indicated that the radiotherapy with prednisone treatment not only is quite effective but also will not result in a significantly increased rate of distant metastasis.
作者对1964年4月至1989年5月期间收治的61例鼻咽癌（NPC）合并皮肌炎（DM）患者进行了研究，这些患者占该医院所有恶性肿瘤的0.027%（61/226,183），占同期鼻咽癌病例的0.086%（61/70,899）。我们分析了45例数据完整的病例，并以年龄、性别和分期匹配的仅患鼻咽癌的病例作为对照。研究结果显示，鼻咽癌合并皮肌炎患者的5年和10年生存率及远处转移率分别为50.4%、34.5%和40.5%，而对照组分别为57.8%、55.2%和56.5%。结果表明，放疗联合泼尼松治疗不仅相当有效，而且不会导致远处转移率显著增加。
