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特发性肺含铁血黄素沉着症:累及肺部的贫血的一个不常见病例。

Idiopathic Pulmonary Haemosiderosis: An Unusual Case Of Anaemia With Pulmonary Involvement.

机构信息

Department of Paediatric Intensive Care Unit, National Institute of Child Health, Karachi, Pakistan.

4th Year MBBS Student, Aga Khan University, Karachi, Pakistan.

出版信息

J Pak Med Assoc. 2023 Aug;73(8):1729-1731. doi: 10.47391/JPMA.7323.

Abstract

Idiopathic pulmonary haemosiderosis is a rare disorder, with recurrent life-threatening alveolar haemorrhages and chronic lung parenchymal changes. It is associated with a triad of haemoptysis, iron deficiency anaemia, and diffuse pulmonary infiltrates. Although most cases are idiopathic, secondary haemosiderosis linked to known diseases has also been observed. Most of the cases remain undiagnosed because the disease is very low on the list of differentials. There is no specified age for the disease. The present study reports on an adolescent female patient who presented with microcytic anaemia and bilateral lung infiltrates to the National Institute of Child Health (NICH), Karachi, a tertiary care hospital. She was diagnosed with Idiopathic pulmonary haemosiderosis after ruling out other possibilities.

摘要

特发性肺含铁血黄素沉着症是一种罕见疾病,其特征为反复发作的危及生命的肺泡出血和慢性肺实质改变。它与三联征,即咯血、缺铁性贫血和弥漫性肺浸润有关。虽然大多数病例是特发性的,但也观察到与已知疾病相关的继发性含铁血黄素沉着症。由于该疾病在鉴别诊断中非常少见,大多数病例仍未得到诊断。该疾病没有特定的发病年龄。本研究报告了一例在卡拉奇国家儿童健康研究所(NICH)就诊的青少年女性患者,她表现为小细胞性贫血和双侧肺浸润。在排除其他可能性后,她被诊断为特发性肺含铁血黄素沉着症。

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