Lin Miao, Zhang Ming-Jian, Fan Xi-Sheng, Zhang Xi-Fen, Liu Jin, Lu Guang-Tong, Chen Hao, Zuo Guang, Liu Jun, Zhang Jun-Cha, She Yan-Fen
College of Acupuncture-Moxibustion and Tuina, Hebei University of TCM, Shijiazhuang 050200, China.
Beijing Jingmei Group General Hospital.
Zhongguo Zhen Jiu. 2023 Sep 12;43(9):1042-7. doi: 10.13703/j.0255-2930.20221227-k0005.
To observe the skin surface microcirculation of acupoints of conception vessel, governor vessel and thoroughfare vessel in patients with primary dysmenorrhea using laser speckle contrast imaging (LSCI), and provide acupoint selection basis of acupuncture-moxibustion for primary dysmenorrhea.
Ninety-nine healthy female college students with regular menstrual cycles (normal group) and 94 female college students with primary dysmenorrhea (dysmenorrhea group) were recruited. Before menstrual period, on the first day of menstruation, and on the third day after menstruation, LSCI was used to observe the surface microcirculation at the abdominal acupoints of conception vessel, i. e. Yinjiao (CV 7), Qihai (CV 6), Shimen (CV 5), Guanyuan (CV 4), Zhongji (CV 3) and Qugou (CV 2), acupoints of thoroughfare vessel, i. e. Huangshu (KI 16), Zhongzhu (KI 15), Siman (KI 14), Qixue (KI 13), Dahe (KI 12), Henggu (KI 11) and acupoints of lumbosacral region of governor vessel, i. e. Xuanshu (GV 5), Mingmen (GV 4), Yaoyangguan (GV 3), Yaoshu (GV 2) as well as two non-acupoints.
Before menstrual period, there was no significant difference in the surface blood perfusion of the acupoints between the dysmenorrhea group and the normal group (>0.05). On the first day of menstruation, the surface blood perfusion of Xuanshu (GV 5), Mingmen (GV 4), Yaoyangguan (GV 3) and right Huangshu (KI 16) in the dysmenorrhea group was higher than that in the normal group (<0.05, <0.01). On the third day after menstruation, the surface blood perfusion of the right Henggu (KI 11) in the dysmenorrhea group was lower than that in the normal group (<0.05).
In patients with primary dysmenorrhea, on the first day of menstruation, the surface blood perfusion of Xuanshu (GV 5), Mingmen (GV 4), Yaoyangguan (GV 3) of governor vessel, and the right Huangshu (KI 16) of thoroughfare vessel is increased, while on the third day after menstruation, the surface blood perfusion of the right Henggu (KI 11) of thoroughfare vessel is decreased. These findings might provide a basis for acupoint selection in the acupuncture-moxibustion treatment of primary dysmenorrhea.
采用激光散斑对比成像（LSCI）观察原发性痛经患者任脉、督脉和冲脉穴位的皮肤表面微循环，为原发性痛经的针灸选穴提供依据。
招募99名月经周期规律的健康女大学生（正常组）和94名原发性痛经女大学生（痛经组）。在月经前、月经第一天和月经后第三天，使用LSCI观察任脉腹部穴位，即阴交（CV7）、气海（CV6）、石门（CV5）、关元（CV4）、中极（CV3）和曲骨（CV2），冲脉穴位，即肓俞（KI16）、中注（KI15）、四满（KI14）、气穴（KI13）、大赫（KI12）、横骨（KI11）以及督脉腰骶部穴位，即悬枢（GV5）、命门（GV4）、腰阳关（GV3）、腰俞（GV2）以及两个非穴位处的表面微循环。
月经前，痛经组与正常组穴位表面血灌注无显著差异（>0.05）。月经第一天，痛经组悬枢（GV5）、命门（GV4）、腰阳关（GV3）及右侧肓俞（KI16）的表面血灌注高于正常组（<0.05，<0.01）。月经后第三天，痛经组右侧横骨（KI11）的表面血灌注低于正常组（<0.05）。
原发性痛经患者在月经第一天，督脉的悬枢（GV5）、命门（GV4）、腰阳关（GV3）及冲脉的右侧肓俞（KI16）表面血灌注增加，而在月经后第三天，冲脉的右侧横骨（KI11）表面血灌注降低。这些发现可能为原发性痛经的针灸治疗选穴提供依据。
