Klein E, Trautmann M, Hoffmann H G
Dtsch Med Wochenschr. 1986 Oct 17;111(42):1599-602. doi: 10.1055/s-2008-1068678.
Ten patients - two with Salmonella septicaemia associated with AIDS; one each Salmonella excretors in the convalescence stage and with Salmonella osteomyelitis; three with abdominal typhoid, and three with Salmonella enteritis - were treated with the gyrase inhibitor ciprofloxacin. The drug was given for 3-33 days, at a dosage of 250-750 mg orally in most cases. Clinical and bacteriological cure was achieved in nine patients. There were no significant side effects. One patient developed a macular rash, which is within the usual side-effect rate.
10名患者——2名患有与艾滋病相关的沙门氏菌败血症;1名处于恢复期的沙门氏菌排泄者和1名患有沙门氏菌骨髓炎;3名患有伤寒,3名患有沙门氏菌肠炎——接受了喹诺酮类抑制剂环丙沙星治疗。药物治疗3至33天,大多数情况下口服剂量为250至750毫克。9名患者实现了临床和细菌学治愈。没有明显副作用。1名患者出现斑疹,这在常见副作用发生率范围内。