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环丙沙星治疗沙门氏菌感染及腹型伤寒

[Ciprofloxacin in Salmonella infection and abdominal typhoid].

作者信息

Klein E, Trautmann M, Hoffmann H G

出版信息

Dtsch Med Wochenschr. 1986 Oct 17;111(42):1599-602. doi: 10.1055/s-2008-1068678.

DOI:10.1055/s-2008-1068678
PMID:3769803
Abstract

Ten patients - two with Salmonella septicaemia associated with AIDS; one each Salmonella excretors in the convalescence stage and with Salmonella osteomyelitis; three with abdominal typhoid, and three with Salmonella enteritis - were treated with the gyrase inhibitor ciprofloxacin. The drug was given for 3-33 days, at a dosage of 250-750 mg orally in most cases. Clinical and bacteriological cure was achieved in nine patients. There were no significant side effects. One patient developed a macular rash, which is within the usual side-effect rate.

摘要

10名患者——2名患有与艾滋病相关的沙门氏菌败血症;1名处于恢复期的沙门氏菌排泄者和1名患有沙门氏菌骨髓炎;3名患有伤寒,3名患有沙门氏菌肠炎——接受了喹诺酮类抑制剂环丙沙星治疗。药物治疗3至33天,大多数情况下口服剂量为250至750毫克。9名患者实现了临床和细菌学治愈。没有明显副作用。1名患者出现斑疹,这在常见副作用发生率范围内。

相似文献

1
[Ciprofloxacin in Salmonella infection and abdominal typhoid].环丙沙星治疗沙门氏菌感染及腹型伤寒
Dtsch Med Wochenschr. 1986 Oct 17;111(42):1599-602. doi: 10.1055/s-2008-1068678.
2
Ciprofloxacin in enteric fever.环丙沙星治疗肠热症
Chemioterapia. 1987 Jun;6(2 Suppl):492-3.
3
Ciprofloxacin in the elimination of enteric Salmonella carriage stage.环丙沙星用于消除肠道沙门氏菌携带阶段。
Scand J Infect Dis Suppl. 1989;60:112-5.
4
[Ciprofloxacin: a solution for recurrent bacteremia caused by Salmonella non typhi in acquired immunodeficiency syndrome?].环丙沙星:是获得性免疫缺陷综合征中非伤寒沙门氏菌引起的复发性菌血症的一种解决方案吗?
Enferm Infecc Microbiol Clin. 1989 Oct;7(8):449-50.
5
[Ofloxacin treatment of salmonella infections].
Mikrobiyol Bul. 1993 Jul;27(3):228-32.
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Ciprofloxacin-resistant Salmonella enterica serotype typhi in a patient with osteomyelitis of the rib.一名患有肋骨骨髓炎患者体内的耐环丙沙星伤寒沙门氏菌肠炎血清型菌株
Med J Malaysia. 2005 Dec;60(5):667-9.
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Salmonella gas-forming femoral osteomyelitis and pyomyositis: the first case and review of the literature.产气性沙门氏菌所致股骨骨髓炎和脓性肌炎:首例病例及文献综述
J Med Assoc Thai. 2007 Sep;90(9):1943-7.
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Ciprofloxacin treatment of chronic Salmonella excretors.环丙沙星治疗慢性沙门氏菌排泄者。
Chemioterapia. 1987 Jun;6(2 Suppl):485-6.
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Septicaemia caused by an imported strain of multiply antibiotic resistant Salmonella typhi successfully treated with ciprofloxacin.
Trop Geogr Med. 1990 Oct;42(4):370-2.
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[Effect of ciprofloxacin therapy in duration of bacterial excretion in acute salmonella gastroenteritis].环丙沙星治疗对急性沙门氏菌胃肠炎细菌排泄持续时间的影响
Schweiz Med Wochenschr. 1993 Oct 16;123(41):1935-40.

引用本文的文献

1
Ciprofloxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.环丙沙星:抗菌活性、药代动力学特性及治疗用途综述
Drugs. 1988 Apr;35(4):373-447. doi: 10.2165/00003495-198835040-00003.
2
Worldwide clinical data on efficacy and safety of ciprofloxacin.
Infection. 1988;16 Suppl 1:S29-43. doi: 10.1007/BF01650504.
3
Oral ciprofloxacin treatment for Salmonella typhimurium infection of normal and immunocompromised mice.口服环丙沙星治疗正常小鼠和免疫功能低下小鼠的鼠伤寒沙门氏菌感染。
Antimicrob Agents Chemother. 1988 Jan;32(1):57-62. doi: 10.1128/AAC.32.1.57.