State Key Laboratory of Cardiovascular Disease, FuWai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, PR China.
Beijing Star Medical Devices Co., Ltd., Beijing, PR China.
Int J Artif Organs. 2023 Oct-Nov;46(10-11):569-573. doi: 10.1177/03913988231192118. Epub 2023 Sep 12.
We aimed to elucidate the effects of the micro-structure of the pyrolytic carbon for artificial heart valves on its hydrodynamic performance.
Bileaflet mechanical valves of GKS 23 and 29 A were randomly selected. According to ISO5840, mean transvalvular pressure (MPG), regurgitation fraction (RF), and effective orifice area (EOA) of valve were assessed. Then, parallel-groove pattern was constructed by laser etching on leaflet surface, and the valves were subjected again to the same test.
Compared with before patterning at 2, 3.5, 5, and 7 L/min, the MPG of the valves in two specifications were higher, the EOA was larger in 23 A, but smaller in 29 A, and the RF was contrary to EOA. At 5 L/min, the RF in both specifications was lower after etching at 45 bpm. At 70 bpm however, the RF in 23 A decreased, in 29 A increased.
The parallel-groove pattern on leaflet surface affected the hemodynamic performance of the valve prostheses.
阐明人工心脏瓣膜热解碳微观结构对其流体动力性能的影响。
随机选择 GKS 23 和 29A 双叶机械瓣膜。根据 ISO5840，评估瓣膜的平均跨瓣压（MPG）、反流分数（RF）和有效瓣口面积（EOA）。然后，通过激光在叶片表面上刻蚀平行槽图案，并再次对瓣膜进行相同的测试。
与未图案化相比，在 2、3.5、5 和 7 L/min 时，两种规格的瓣膜 MPG 更高，23A 的 EOA 更大，但 29A 的 EOA 更小，RF 与 EOA 相反。在 45 bpm 时，两种规格的 RF 在 5 L/min 时均降低。然而，在 70 bpm 时，23A 的 RF 降低，29A 的 RF 升高。
叶片表面的平行槽图案影响了瓣膜假体的血液动力学性能。
