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[原发性腹膜后肿瘤]

[Primary retroperitoneal tumors].

作者信息

Frilling A, Grabitz K, Nier H

出版信息

Dtsch Med Wochenschr. 1986 Oct 24;111(43):1636-41. doi: 10.1055/s-2008-1068684.

Abstract

73 patients, 41 males and 32 females, were treated for primary retroperitoneal tumours between 1974 and 1984. Mean age of the patients was 45.9 years (range: 1 day-79 years). Early symptoms of the tumours were atypical. Initial diagnosis showed a palpable abdominal tumour in 47 patients. Computed tomography is the most important radiologic tool for the diagnosis. In 32 patients the tumour could be removed completely. Intraoperatively, at least one additional organ had to be removed in all patients to ensure radicality of extirpation. Histology showed most tumours to be lymphomas or sarcomas. At the time of diagnosis, 21 patients were found to have metastases. Operative mortality rate was 11%. The overall prognosis in patients with primary retroperitoneal tumours is poor; the 5-year survival rate for malignant tumors was 9%. Combination of radio- and chemotherapy has somewhat improved this dim prognosis in recent years.

摘要

1974年至1984年间,73例原发性腹膜后肿瘤患者接受了治疗,其中男性41例,女性32例。患者的平均年龄为45.9岁(范围:1天至79岁)。肿瘤的早期症状不典型。初诊时,47例患者可触及腹部肿块。计算机断层扫描是诊断最重要的影像学工具。32例患者的肿瘤得以完全切除。术中,为确保切除彻底,所有患者至少还需切除一个额外器官。组织学检查显示,大多数肿瘤为淋巴瘤或肉瘤。诊断时,21例患者已出现转移。手术死亡率为11%。原发性腹膜后肿瘤患者的总体预后较差;恶性肿瘤的5年生存率为9%。近年来,放疗和化疗联合应用在一定程度上改善了这一黯淡的预后。

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