Kairaluoma M I, Krause-Mäkitalo B, Pokela R, Ståhlberg M, Laitinen S, Mokka R E
Ann Chir Gynaecol. 1984;73(6):313-8.
48 patients underwent operation for a primary retroperitoneal tumour during the years 1962 to 1983. Palpable abdominal mass and abdominal pain were the most common presenting symptoms. Computerized tomography complemented by cavography, aortography and intravenous pyelography were the most effective radiological investigations available. 35 (73%) of the 48 tumours were malignant but only 8/35 (17%) of them had local metastases. 11 (23%) of the 48 tumours were radically excised, 20/48 (42%) had partial excision and 17/48 (35%) an incisional biopsy. 4 (11%) of the 35 malignant tumours were excised radically, 16/35 (46%) were partially excised and 15/35 (43%) had an incisional biopsy. Resection of adjacent organs was performed in 8 patients (17%). Overall operative mortality was 15% and morbidity 23%. All mortality in patients with malignant tumours occurred after incisional biopsy. Prognosis of benign tumours was excellent. The 5-year cumulative survival for malignant tumours was 28 +/- 9%. 7 patients were alive 5 years after operation but only 2 of them without evidence of recurrent disease. In conclusion, long-term results obtained by surgery of malignant tumours were less satisfactory. Hence, randomized trials with adjuvant radiation and chemotherapy are necessary. Local recurrences should be diagnosed early and resected aggressively.
1962年至1983年间，48例患者因原发性腹膜后肿瘤接受了手术。可触及的腹部肿块和腹痛是最常见的首发症状。计算机断层扫描辅以腔静脉造影、主动脉造影和静脉肾盂造影是最有效的影像学检查方法。48例肿瘤中35例（73%）为恶性，但其中只有8/35（17%）发生了局部转移。48例肿瘤中11例（23%）被根治性切除，20/48（42%）行部分切除，17/48（35%）行切开活检。35例恶性肿瘤中4例（11%）被根治性切除，16/35（46%）行部分切除，15/35（43%）行切开活检。8例患者（17%）切除了相邻器官。总体手术死亡率为15%，发病率为23%。恶性肿瘤患者的所有死亡均发生在切开活检后。良性肿瘤的预后极好。恶性肿瘤的5年累积生存率为28±9%。7例患者术后存活5年，但其中只有2例无复发迹象。总之，恶性肿瘤手术的长期效果不太令人满意。因此，有必要进行辅助放疗和化疗的随机试验。局部复发应早期诊断并积极切除。
