猫母体牛磺酸缺乏：对后代视网膜和反光膜的影响。

Feline maternal taurine deficiency: effects on retina and tapetum of the offspring.

作者信息

Imaki H, Moretz R C, Wisniewski H M, Sturman J A

出版信息

Dev Neurosci. 1986;8(3):160-81. doi: 10.1159/000112251.

Abstract

The retina and tapetum of kittens born to taurine-deficient and taurine-supplemented mothers were compared. Retinal taurine concentrations typically reach adult levels 6 weeks postnatally. When measured at weaning at 8 postnatal weeks, the taurine concentrations in retina and tapetum of taurine-deficient kittens were 40% of normal levels. An ultrastructural correlate found in the retinas of taurine-deficient kittens was the presence of photoreceptor outer segments that were reduced in length and altered from the typical columnar configuration. Tapetal cells of taurine-deficient kittens were distinguished by accumulations of electron-dense droplets, the presence of tapetal rods with dilated limiting membranes and the presence of amorphous vesicles.

摘要

对牛磺酸缺乏和补充牛磺酸的母猫所生小猫的视网膜和反光层进行了比较。视网膜牛磺酸浓度通常在出生后6周达到成年水平。在出生后8周断奶时测量，牛磺酸缺乏小猫的视网膜和反光层中的牛磺酸浓度为正常水平的40%。在牛磺酸缺乏小猫的视网膜中发现的超微结构相关特征是光感受器外段长度缩短，且从典型的柱状结构改变。牛磺酸缺乏小猫的反光层细胞的特征是有电子致密液滴的积累、有界限膜扩张的反光层杆以及有无定形囊泡。