J Am Geriatr Soc. 2023 Dec;71(12):3792-3801. doi: 10.1111/jgs.18552. Epub 2023 Sep 12.
How psychological resilience influences postoperative outcomes remains poorly characterized. We tested the hypothesis that psychological resilience is associated with lower odds of death or new inability to walk independently and other outcomes at 60 days after hip fracture surgery.
This was a pre-planned secondary analysis of a multicenter randomized trial comparing spinal versus general anesthesia for hip fracture surgery. We analyzed data on 1360 adults aged 50 years or older who were hospitalized for hip fracture surgery at one of 46 US or Canadian hospitals and provided psychological resilience data preoperatively as measured via the Brief Resilience Scale. Major exclusions were the inability to walk without human assistance before fracture and contraindications to spinal anesthesia. Death or new inability to walk independently at 60 days after surgery was the primary outcome; death or new nursing home residence at 60 days and 60-day mortality were secondary outcomes.
Greater psychological resilience was associated with lower odds of death or new inability to walk at day 60 (adjusted odds ratio [aOR] 0.77; 95% Confidence Interval [CI], 0.61 to 0.98; p = 0.03). We observed a similar association between psychological resilience and outcomes among patients who did not experience complications after surgery (aOR 0.72; CI 0.55 to 0.94, p = 0.02), but not those who had complications (aOR 1.00; CI 0.59 to 1.69, p = 0.99). Psychological resilience was associated with lower odds of 60-day death or new nursing home residence (aOR 0.73; 95% CI 0.58 to 0.93; p < 0.001) but not with 60-day mortality (aOR 0.92; 95% CI 0.56 to 1.49; p = 0.73).
Psychological resilience is associated with better outcomes for older adults after hip fracture surgery, but largely among those who do not have postoperative complications. Future interventions may focus on improving psychological resilience preoperatively or providing support to patients with lower psychological resilience.
心理韧性如何影响术后结果仍未得到充分描述。我们检验了这样一个假设,即心理韧性与髋部骨折手术后60天时死亡或新出现的无法独立行走及其他结果的较低几率相关。
这是一项对多中心随机试验的预先计划的二次分析,该试验比较了髋部骨折手术中脊髓麻醉与全身麻醉。我们分析了在美国或加拿大46家医院之一因髋部骨折手术住院的1360名50岁及以上成年人的数据,这些人在术前通过简易韧性量表提供了心理韧性数据。主要排除标准是骨折前无法在无他人协助下行走以及脊髓麻醉的禁忌症。手术后60天时死亡或新出现的无法独立行走是主要结局;60天时死亡或新入住养老院以及60天死亡率是次要结局。
更高的心理韧性与60天时死亡或新出现的无法行走的较低几率相关(调整后的优势比[aOR]为0.77;95%置信区间[CI],0.61至0.98;p = 0.03)。我们在术后未出现并发症的患者中观察到心理韧性与结局之间存在类似关联(aOR 0.72;CI 0.55至0.94,p = 0.02),但在出现并发症的患者中未观察到(aOR 1.00;CI 0.59至1.69,p = 0.99)。心理韧性与60天时死亡或新入住养老院的较低几率相关(aOR 0.73;95% CI 0.58至0.93;p < 0.001),但与60天死亡率无关(aOR 0.92;95% CI 0.56至1.49;p = 0.73)。
心理韧性与髋部骨折手术后老年人的更好结局相关,但主要是在那些没有术后并发症的人群中。未来的干预措施可能侧重于术前改善心理韧性或为心理韧性较低的患者提供支持。