Charles G, Mirel J, Lefevre A
Encephale. 1986 May-Jun;12(3):105-10.
Sixty-four nondepressed, carefully selected senile demented inpatients underwent two 1.0 mg overnight dexamethasone suppression tests (DSTs) separated by 7 days. These patients had been in a clinically stable and drug-free state for at least six months prior to testing. The Modified Ischemic Scale score and ICD-9 criteria for Alzheimer's disease were used to dichotomize subjects into Alzheimer's and multi-infarct types of dementia. Patients with vascular dementias were significantly more likely to evidence DST nonsuppression, furthermore, DSTs in this group were less reproducible from week to week than DSTs in Alzheimer's patients.
64名经过精心挑选的非抑郁老年痴呆住院患者接受了两次1.0毫克的夜间地塞米松抑制试验（DST），两次试验间隔7天。这些患者在测试前至少六个月处于临床稳定且未服用药物的状态。采用改良缺血量表评分和阿尔茨海默病的国际疾病分类第九版（ICD - 9）标准，将受试者分为阿尔茨海默病型和多发梗死型痴呆。血管性痴呆患者出现DST不抑制的可能性显著更高，此外，该组患者的DST每周之间的可重复性低于阿尔茨海默病患者的DST。
