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癫痫患者隐瞒病情对药物依从性的影响:一项横断面研究。

The effects of concealment of epilepsy on medication adherence in people with epilepsy: A cross-sectional study.

机构信息

Siirt University, Faculty of Health Sciences, Department of Internal Medicine Nursing, Siirt, Turkey.

Siirt University, Faculty of Health Sciences, Department of Nursing Fundamentals, Siirt, Turkey.

出版信息

Epilepsy Res. 2023 Oct;196:107220. doi: 10.1016/j.eplepsyres.2023.107220. Epub 2023 Sep 1.

Abstract

AIM

Adherence to antiseizure medication is of great importance in achieving seizure control and maintaining well-being for people with epilepsy. Therefore, it is important to assess medication adherence and factors affecting medication adherence in this patient group. This study aims to examine the effects of concealment of epilepsy on medication adherence in people with epilepsy.

METHOD

This cross-sectional study was conducted with 220 people with epilepsy. Data were collected using a patient information form, the Morisky Medication Adherence Scale-8 (MMAS-8), and the Concealment of Epilepsy Scale (CES) and analyzed using descriptive statistics and multiple linear regression analysis.

RESULTS

The mean age of the participants was 49.84 ± 9.43 years, and 53.6% of them were male. Their mean MMAS-8 score was 4.25 ± 1.99%, and 72.3% had low medication adherence. Additionally, their mean CES score was 49.84 ± 9.43. The CES scores of the participants negatively predicted their MMAS-8 scores (p < 0.05), and medication adherence was positively predicted by female gender, the duration of diagnosis, the single administration of drugs per day, and employment status, whereas it was negatively predicted by the annual number of seizures (F=19.256, p < 0.001).

CONCLUSION

In this study, people with epilepsy were found to have low medication adherence and a high tendency to conceal epilepsy. Furthermore, the tendency to conceal epilepsy had a negative effect on medication adherence.

IMPLICATIONS

Psychosocial interventions aimed at reducing the tendency to conceal epilepsy can contribute to medication adherence in people with the condition.

摘要

目的

抗癫痫药物的依从性对于控制癫痫发作和提高癫痫患者的生活质量至关重要。因此,评估该患者群体的药物依从性及其影响因素非常重要。本研究旨在探讨癫痫患者隐瞒病情对药物依从性的影响。

方法

本横断面研究纳入了 220 名癫痫患者。通过患者信息表、Morisky 药物依从性量表-8(MMAS-8)和癫痫隐瞒量表(CES)收集数据,并采用描述性统计和多元线性回归分析进行分析。

结果

参与者的平均年龄为 49.84±9.43 岁,其中 53.6%为男性。他们的 MMAS-8 平均得分为 4.25±1.99%,72.3%的患者药物依从性较低。此外,他们的 CES 平均得分为 49.84±9.43。CES 评分与 MMAS-8 评分呈负相关(p<0.05),女性、诊断年限、每日服药次数、就业状态与药物依从性呈正相关,而年癫痫发作次数与药物依从性呈负相关(F=19.256,p<0.001)。

结论

本研究发现,癫痫患者的药物依从性较低,且有隐瞒病情的倾向。此外,隐瞒病情的倾向对药物依从性有负面影响。

意义

旨在减少隐瞒病情倾向的心理社会干预措施,可能有助于提高癫痫患者的药物依从性。

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