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HIV/性传播感染筛查和符合条件的女性囚犯接受 HIV 暴露前预防。

HIV/Sexually Transmitted Infection Screening and Eligibility for HIV Preexposure Prophylaxis Among Women Incarcerated in an Urban County Jail.

机构信息

From the Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX.

Beth Israel Deaconess Medical Center, Boston, MA.

出版信息

Sex Transm Dis. 2023 Oct 1;50(10):675-679. doi: 10.1097/OLQ.0000000000001852. Epub 2023 Jul 19.

DOI:10.1097/OLQ.0000000000001852
PMID:37699368
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10503027/
Abstract

BACKGROUND

Incarcerated women experience high rates of HIV and sexually transmitted infections (STIs); few are offered HIV preexposure prophylaxis (PrEP). We aimed to examine HIV/STI screening rates in this population and identify PrEP eligibility.

METHODS

Results of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (GC) urine and HIV/syphilis screening in cisgender women in the Dallas County Jail were compiled from January to October 2020. An electronic health record review was conducted for a subgroup in March 2020 to identify PrEP eligibility.

RESULTS

Overall, 4398 of 13,292 women were screened for CT and 4389 of 13,292 for GC, and among them, 479 (11%) screened for HIV and 562 (13%) for syphilis. Furthermore, 462 of 4398 (11%) were positive for CT, 323 of 4389 (7%) were positive for GC, 10 of 479 (2%) had positive HIV test results, of whom 6 (1.3%) were new diagnoses and 75 (13%) had a reactive rapid plasma reagin test. In March 2020, of 541 women screened, 90 tested positive for CT or GC. Of these 90, 70 (78%) did not receive HIV or syphilis screening, including women with these risk factors: 10 (14%) were homeless, 11 (16%) reported heroin use, and 10 (14%) reported methamphetamine use. Based on the presence of an acute bacterial STI, 17% (96 of 541) were PrEP eligible.

CONCLUSIONS

Incarcerated women had high STI rates and other risk factors for HIV acquisition, although only 1 in 5 with acute STIs (11% overall) was also screened for HIV or syphilis. HIV prevention efforts should include comprehensive STI/HIV screening, linkage to treatment, and identification of PrEP candidates.

摘要

背景

被监禁的女性感染艾滋病毒和性传播感染(STIs)的比率很高;很少有女性接受艾滋病毒暴露前预防(PrEP)。我们旨在研究这一人群中的艾滋病毒/性传播感染筛查率,并确定 PrEP 的资格。

方法

2020 年 1 月至 10 月,收集了达拉斯县监狱中顺性别女性的沙眼衣原体(CT)和淋病奈瑟菌(GC)尿液和艾滋病毒/梅毒筛查结果。2020 年 3 月,对一个亚组进行了电子病历审查,以确定 PrEP 的资格。

结果

总体而言,13292 名女性中有 4398 人接受了 CT 筛查,13292 人中有 4389 人接受了 GC 筛查,其中 479 人(11%)接受了艾滋病毒筛查,562 人(13%)接受了梅毒筛查。此外,4398 人中 462 人(11%)CT 检测阳性,4389 人中 323 人(7%)GC 检测阳性,479 人中 10 人(2%)艾滋病毒检测阳性,其中 6 人(1.3%)为新诊断,75 人(13%)快速血浆反应素试验阳性。2020 年 3 月,在 541 名接受筛查的女性中,90 人 CT 或 GC 检测阳性。在这 90 人中,有 70 人(78%)未接受艾滋病毒或梅毒筛查,包括有以下风险因素的女性:10 人(14%)无家可归,11 人(16%)报告使用海洛因,10 人(14%)报告使用冰毒。根据急性细菌性 STI 的存在,有 17%(541 人中有 96 人)符合 PrEP 资格。

结论

被监禁的女性 STI 发病率和其他艾滋病毒感染的风险因素很高,尽管只有 1/5 有急性 STI(总体 11%)的人也接受了艾滋病毒或梅毒筛查。艾滋病毒预防工作应包括全面的性传播感染/艾滋病毒筛查、与治疗的联系以及确定 PrEP 候选人。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81fa/10503027/284b7c505388/nihms-1917136-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81fa/10503027/284b7c505388/nihms-1917136-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81fa/10503027/284b7c505388/nihms-1917136-f0001.jpg

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