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重新定义预防与护理:一种对艾滋病毒的无状态方法。

Redefining Prevention and Care: A Status-Neutral Approach to HIV.

作者信息

Myers Julie E, Braunstein Sarah L, Xia Qiang, Scanlin Kathleen, Edelstein Zoe, Harriman Graham, Tsoi Benjamin, Andaluz Adriana, Yu Estella, Daskalakis Demetre

机构信息

Bureau of HIV/AIDS Prevention and Control, New York City Department of Health and Mental Hygiene, New York, New York.

Division of Infectious Diseases, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York.

出版信息

Open Forum Infect Dis. 2018 May 2;5(6):ofy097. doi: 10.1093/ofid/ofy097. eCollection 2018 Jun.

Abstract

Recent biomedical advances inspire hope that an end to the epidemic of HIV is in sight. Adopting new approaches and paradigms for treatment and prevention in terms of both messaging and programming is a priority to accelerate progress. Defining the key sequential steps that comprise engagement in HIV care has provided a useful framework for clinical programs and motivated quality improvement initiatives. Recently, the same approach has been applied to use of pre-exposure prophylaxis for HIV prevention. Building on the various prevention and care continua previously proposed, we present a novel schematic that incorporates both people living with HIV and people at risk, making it effectively "status-neutral" in that it proposes the same approach for engagement, regardless of one's HIV status. This multidirectional continuum begins with an HIV test and offers 2 divergent paths depending on the results; these paths end at a common final state. To illustrate how this continuum can be utilized for program planning as well as for monitoring, we provide an example using data for New York City men who have sex with men, a population with high HIV incidence and prevalence.

摘要

近期生物医学的进展让人们燃起希望,认为艾滋病流行有望终结。在信息传播和项目规划方面采用新的治疗与预防方法及模式,是加速进展的当务之急。明确构成参与艾滋病护理的关键连续步骤,为临床项目提供了有用框架,并推动了质量改进举措。最近,同样的方法已应用于艾滋病暴露前预防。在先前提出的各种预防和护理连续统一体的基础上,我们提出了一个新颖的示意图,将艾滋病病毒感染者和有风险人群都纳入其中,使其在实际上“不考虑感染状况”,因为无论一个人的艾滋病病毒感染状况如何,它都提出相同的参与方法。这个多方向的连续统一体从艾滋病检测开始,根据检测结果提供两条不同的路径;这些路径在一个共同的最终状态结束。为说明这个连续统一体如何用于项目规划以及监测,我们提供一个使用纽约市男男性行为者数据的例子,这是一个艾滋病发病率和患病率都很高的人群。

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