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结肠动力与灌肠剂扩散。

Colonic motility and enema spreading.

作者信息

Hardy J G, Wood E, Clark A G, Reynolds J R

出版信息

Eur J Nucl Med. 1986;12(4):176-8. doi: 10.1007/BF00256916.

DOI:10.1007/BF00256916
PMID:3769964
Abstract

Radiolabelled enema solution was administered to eight healthy subjects, both in fasted and fed states. Enema spreading was monitored over a 4-h period using gamma scintigraphy and colonic motility was recorded simultaneously using a pressure sensitive radiotelemetry capsule. The rate and extent of enema dispersion were unaffected by eating. Spreading could be correlated with colonic motility and was inhibited by aboral propulsion of the colonic contents.

摘要

给八名健康受试者在空腹和进食状态下均施用放射性标记的灌肠液。使用γ闪烁扫描术在4小时内监测灌肠液的扩散情况,并同时使用压敏无线电遥测胶囊记录结肠动力。灌肠液的扩散速率和程度不受进食的影响。扩散情况可能与结肠动力相关,并且会受到结肠内容物逆向推进的抑制。

相似文献

1
Colonic motility and enema spreading.结肠动力与灌肠剂扩散。
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2
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Clin Pharmacokinet. 1991 Aug;21(2):110-28. doi: 10.2165/00003088-199121020-00003.
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Spread and distribution of 5-ASA colonic foam and 5-ASA enema in patients with ulcerative colitis.5-氨基水杨酸结肠泡沫剂和5-氨基水杨酸灌肠剂在溃疡性结肠炎患者中的扩散与分布。
Dig Dis Sci. 1992 Dec;37(12):1890-7. doi: 10.1007/BF01308084.

本文引用的文献

1
Motor responses of human gastrointestinal tract to 5-hydroxytryptamine in vivo and in vitro.人体胃肠道对5-羟色胺的体内及体外运动反应
Gut. 1966 Jun;7(3):208-16. doi: 10.1136/gut.7.3.208.
2
Propulsion (mass movements) in the human colon and its relationship to meals and somatic activity.人类结肠的推进运动(集团蠕动)及其与进餐和躯体活动的关系。
Gut. 1970 Feb;11(2):91-9. doi: 10.1136/gut.11.2.91.
3
Factors controlling colonic motility: colonic pressures and transit after meals in patients with total gastrectomy, pernicious anaemia or duodenal ulcer.
控制结肠运动的因素:全胃切除术、恶性贫血或十二指肠溃疡患者餐后的结肠压力与转运
Gut. 1970 Feb;11(2):100-10. doi: 10.1136/gut.11.2.100.
4
Enema volume as an important factor in successful topical corticosteroid treatment of colitis.灌肠液量是局部使用皮质类固醇成功治疗结肠炎的一个重要因素。
Proc R Soc Med. 1974 Aug;67(8):753-4. doi: 10.1177/003591577406700831.
5
Effect of eating and gastrointestinal hormones on human colonic myoelectrical and motor activity.饮食及胃肠激素对人体结肠肌电活动和运动活性的影响。
Gastroenterology. 1978 Sep;75(3):373-8.
6
Retrograde spread of hydrocortisone containing foam given intrarectally in ulcerative colitis.溃疡性结肠炎患者经直肠给予含氢化可的松泡沫剂的逆行扩散情况。
Br Med J. 1979 Oct 6;2(6194):822-4. doi: 10.1136/bmj.2.6194.822.