L-谷氨酸发酵生产关键技术创新与工业应用
[Innovation of key technologies in fermentative production of L-glutamate and industrial application].
作者信息
Li Xuepeng, Chen Jiuzhou, Zhang Dongxu, Li Shubiao, Wang Xiaoping, Lü Jindong, Zhou Jing, Xu Zhiying, Zheng Ping, Sun Jibin
机构信息
Key Laboratory of Bio-Fermentation Energy Saving and Environmental Protection Technology Enterprise of Inner Mongolia Autonomous Region, Inner Mongollia Fufeng Biotechnologies Co. Ltd., Huhot 010030, Inner Mongolia, China.
Key Laboratory of Systems Microbial Biotechnology, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, China.
出版信息
Sheng Wu Gong Cheng Xue Bao. 2022 Nov 25;38(11):4343-4351. doi: 10.13345/j.cjb.220649.
The fermentative production of L-glutamate is by far the largest among the amino acids commercially produced. L-glutamate is also the largest fermentation product in China in terms of the production scale. With the rapid development in synthetic biotechnology, production equipment and process technologies, the performance of industrial strains and the production technology of L-glutamate have been advanced remarkably in recent years. By analyzing the current situation of L-glutamate industry and the demand for innovation of key technologies, this review summarizes the research progress of L-glutamate production strains and technologies, as well as the development of other key technologies in L-glutamate production and industrial application.
就商业生产的氨基酸而言，L-谷氨酸的发酵生产规模目前是最大的。就生产规模而言，L-谷氨酸也是中国最大的发酵产品。随着合成生物技术、生产设备及工艺技术的快速发展，近年来L-谷氨酸工业菌株的性能及L-谷氨酸生产技术有了显著进步。通过分析L-谷氨酸产业现状及关键技术创新需求，本综述总结了L-谷氨酸生产菌株与技术的研究进展，以及L-谷氨酸生产和工业应用中其他关键技术的发展情况。
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