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S2k 指南:手部湿疹的诊断、预防和治疗。

S2k guideline diagnosis, prevention, and therapy of hand eczema.

机构信息

Department of Dermatology, University Hospital Carl Gustav Carus, Technical University Dresden, Germany.

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Osnabrück, Germany and Institute for Interdisciplinary Dermatologic Prevention and Rehabilitation (iDerm) at the University of Osnabrück, Osnabrück, Germany.

出版信息

J Dtsch Dermatol Ges. 2023 Sep;21(9):1054-1074. doi: 10.1111/ddg.15179.

DOI:10.1111/ddg.15179
PMID:37700424
Abstract

The consensus-based guideline "Diagnosis, prevention, and treatment of hand eczema (HE)" provides concrete instructions and recommendations for diagnosis, prevention, and therapy of HE based on an evidence- and consensus-based approach. The guideline was created based on the German guideline "Management von Handekzemen" from 2009 and the current guideline of the European Society of Contact Dermatitis (ESCD) "Guidelines for diagnosis, prevention, and treatment of hand eczema" from 2022. The general goal of the guideline is to provide dermatologists and allergologists in practice and clinics with an accepted, evidence-based decision-making tool for selecting and conducting suitable and sufficient therapy for patients with hand eczema. The guideline is based on two Cochrane reviews of therapeutic and preventive interventions for HE. The remaining chapters were mainly developed and consented based on non-systematic literature research by the expert group. The expert group consisted of members of allergological and occupational dermatological professional associations and working groups, a patient representative, and methodologists. The proposals for recommendations and key statements were consented by using a nominal group process during a consensus conference on September 15, 2022. The structured consensus-building process was professionally moderated. This guideline is valid until February 22, 2028.

摘要

基于循证和共识的方法,这份共识指南“手部湿疹(HE)的诊断、预防和治疗”为 HE 的诊断、预防和治疗提供了具体的指导和建议。该指南是基于 2009 年德国的指南“手部湿疹管理”和欧洲接触性皮炎学会(ESCD)的现行指南“手部湿疹的诊断、预防和治疗指南”制定的。该指南的总体目标是为皮肤科医生和过敏科医生在实践和诊所中提供一种公认的、基于证据的决策工具,以便为手部湿疹患者选择和进行合适且充分的治疗。该指南基于两项手部湿疹治疗和预防干预的 Cochrane 综述。其余章节主要是由专家组根据非系统性文献研究开发和达成一致的。专家组由过敏和职业性皮肤病专业协会和工作组的成员、一名患者代表和方法学家组成。建议和关键声明的提案是在 2022 年 9 月 15 日的共识会议上通过命名小组过程达成一致的。结构化的共识建立过程由专业人员进行了调解。本指南有效期至 2028 年 2 月 22 日。

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引用本文的文献

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A Practical Approach to Chronic Hand Eczema.慢性手部湿疹的实用治疗方法
Dermatol Ther (Heidelb). 2025 May 18. doi: 10.1007/s13555-025-01433-y.
2
Prevalence, severity and predictors of hand eczema in patients treated for atopic dermatitis: a cross-sectional observational study.特应性皮炎患者手部湿疹的患病率、严重程度及预测因素:一项横断面观察性研究。
Arch Dermatol Res. 2025 Mar 29;317(1):652. doi: 10.1007/s00403-025-04138-6.
3
[Psychological aspects in occupational dermatology].[职业皮肤病学中的心理学方面]
Dermatologie (Heidelb). 2025 Feb;76(2):57-63. doi: 10.1007/s00105-024-05456-y. Epub 2025 Jan 22.
4
Italian Expert Opinion on Chronic Hand Eczema: from Guidelines to Clinical Practice.意大利慢性手部湿疹专家意见:从指南到临床实践
Dermatol Ther (Heidelb). 2025 Jan;15(1):75-93. doi: 10.1007/s13555-024-01312-y. Epub 2024 Nov 28.