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切达干酪衍生生物活性肽的蛋白水解作用及治疗潜力

Proteolysis and therapeutic potential of bioactive peptides derived from Cheddar cheese.

作者信息

Shafique Bakhtawar, Murtaza Mian Anjum, Hafiz Iram, Ameer Kashif, Basharat Shahnai, Mohamed Ahmed Isam A

机构信息

Institute of Food Science and Nutrition University of Sargodha Sargodha Pakistan.

Institute of Chemistry University of Sargodha Sargodha Pakistan.

出版信息

Food Sci Nutr. 2023 Jun 13;11(9):4948-4963. doi: 10.1002/fsn3.3501. eCollection 2023 Sep.

DOI:10.1002/fsn3.3501
PMID:37701240
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10494659/
Abstract

Cheddar cheese-derived bioactive peptides are considered a potential component of functional foods. A positive impact of bioactive peptides on diet-related chronic, non-communicable diseases, like obesity, cardiovascular diseases, and diabetes, has been observed. Bioactive peptides possess multifunctional therapeutic potentials, including antimicrobial, immunomodulatory, antioxidant, enzyme inhibitory effects, anti-thrombotic, and phyto-pathological activities against various toxic compounds. Peptides can regulate human immune, gastrointestinal, hormonal, and neurological responses, which play an integral role in the deterrence and treatment of certain diseases like cancer, osteoporosis, hypertension, and other health disorders, as described in the present review. This review summarizes the categories of the Cheddar cheese-derived bioactive peptides, their general characteristics, physiological functions, and possible applications in healthcare.

摘要

切达干酪衍生的生物活性肽被认为是功能性食品的一种潜在成分。已观察到生物活性肽对与饮食相关的慢性非传染性疾病,如肥胖症、心血管疾病和糖尿病有积极影响。生物活性肽具有多种治疗潜力,包括抗菌、免疫调节、抗氧化、酶抑制作用、抗血栓形成以及针对各种有毒化合物的植物病理活性。肽可以调节人体的免疫、胃肠、激素和神经反应,如本综述所述,这些反应在预防和治疗某些疾病(如癌症、骨质疏松症、高血压和其他健康紊乱)中起着不可或缺的作用。本综述总结了切达干酪衍生的生物活性肽的类别、其一般特性、生理功能以及在医疗保健中的可能应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d578/10494659/735f4f5fa422/FSN3-11-4948-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d578/10494659/a0784109bfd1/FSN3-11-4948-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d578/10494659/fbe65b56761a/FSN3-11-4948-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d578/10494659/735f4f5fa422/FSN3-11-4948-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d578/10494659/a0784109bfd1/FSN3-11-4948-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d578/10494659/fbe65b56761a/FSN3-11-4948-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d578/10494659/735f4f5fa422/FSN3-11-4948-g012.jpg

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