Rouer E, Beaune P, Leroux J P
Experientia. 1986 Oct 15;42(10):1162-3. doi: 10.1007/BF01941293.
Streptozotocin-diabetes in rats leads to a decrease of cytochrome P-450 UT-A (the major form in control rats) and an increase of cytochrome P-450 PB-B (the major one induced by phenobarbital treatment) in liver microsomes. The increased benzphetamine-N-demethylase activity can be related to the induction of cytochrome P-450 PB-B.