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Multiple forms of cytochrome P-450 and the importance of molecular biology and evolution.

作者信息

Nebert D W, Negishi M

出版信息

Biochem Pharmacol. 1982 Jul 15;31(14):2311-7. doi: 10.1016/0006-2952(82)90523-8.

DOI:10.1016/0006-2952(82)90523-8
PMID:6181791
Abstract
摘要

相似文献

1
Multiple forms of cytochrome P-450 and the importance of molecular biology and evolution.细胞色素P-450的多种形式以及分子生物学和进化的重要性。
Biochem Pharmacol. 1982 Jul 15;31(14):2311-7. doi: 10.1016/0006-2952(82)90523-8.
2
Effect of enzyme inducers on substrate specificity of the cytochrome P-450's.酶诱导剂对细胞色素P-450底物特异性的影响。
Drug Metab Dispos. 1973 Jan-Feb;1(1):199-210.
3
Induction of rat hepatic microsomal cytochrome P-450 by 2,3',4,4',5,5'-hexachlorobiphenyl.2,3',4,4',5,5'-六氯联苯对大鼠肝微粒体细胞色素P-450的诱导作用
Biochem Pharmacol. 1983 Jul 15;32(14):2269-79. doi: 10.1016/0006-2952(83)90237-x.
4
Pregnenolone-16alpha-carbonitrile-inducible cytochrome P450 in rat liver.孕烯醇酮-16α-腈诱导的大鼠肝脏细胞色素P450
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5
Evidence for a PCN-P450 enzyme in chickens and comparison of its development with that of other phenobarbital-inducible forms.鸡体内一种PCN-P450酶的证据及其与其他苯巴比妥诱导型形式的发育比较。
Mol Pharmacol. 1989 May;35(5):610-6.
6
Enzyme induction with pregnenolone-16 alpha-carbonitrile--onset of action and effect of thioacetamide.孕烯醇酮-16α-腈的酶诱导作用——硫代乙酰胺的起效时间及效果
Biochem Pharmacol. 1974 Apr 1;23(7):1221-3. doi: 10.1016/0006-2952(74)90298-6.
7
Phenobarbital-inducible gene expression in developing rat liver: relationship to hepatocyte function.苯巴比妥诱导发育中大鼠肝脏的基因表达:与肝细胞功能的关系。
Biochim Biophys Acta. 1989 Dec 22;1009(3):221-8. doi: 10.1016/0167-4781(89)90106-1.
8
A novel haemoprotein induced by isosafrole pretreatment in the rat.
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9
Influence of three inducers on rabbit gamma-glutamyltransferase.三种诱导剂对兔γ-谷氨酰转移酶的影响。
Pharmacol Res Commun. 1980 Jun;12(6):557-65. doi: 10.1016/s0031-6989(80)80141-x.
10
Influence of isoniazid, phenobarbital, phenytoin, pregnenolone 16-alpha carbonitrile, and beta-naphthoflavone on halothane metabolism and hepatotoxicity.异烟肼、苯巴比妥、苯妥英、孕烯醇酮16-α-腈和β-萘黄酮对氟烷代谢及肝毒性的影响。
Drug Metab Dispos. 1990 Sep-Oct;18(5):819-22.

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Modulatory influence of noscapine on the ethanol-altered hepatic biotransformation system enzymes, glutathione content and lipid peroxidation in vivo in rats.那可丁对大鼠体内乙醇改变的肝脏生物转化系统酶、谷胱甘肽含量及脂质过氧化的调节作用。
Eur J Drug Metab Pharmacokinet. 2004 Jul-Sep;29(3):157-62. doi: 10.1007/BF03190592.
2
Molecular genetics of cytochrome P450 IID. Anomalies of drug metabolism.细胞色素P450 IID的分子遗传学。药物代谢异常。
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3
At least six forms of extremely homologous cytochromes P-450 in rat liver are encoded at two closely linked genetic loci.
大鼠肝脏中至少六种形式的高度同源细胞色素P-450是由两个紧密连锁的基因位点编码的。
Proc Natl Acad Sci U S A. 1983 Nov;80(21):6542-6. doi: 10.1073/pnas.80.21.6542.
4
Pharmacogenetics of mephenytoin: a new drug hydroxylation polymorphism in man.美芬妥英的药物遗传学:人类一种新的药物羟基化多态性
Eur J Clin Pharmacol. 1984;26(6):753-9. doi: 10.1007/BF00541938.
5
Identification of increased amounts of UDP-glucuronyltransferase protein in phenobarbital-treated chick-embryo liver cells.在经苯巴比妥处理的鸡胚肝细胞中鉴定出UDP-葡萄糖醛酸基转移酶蛋白含量增加。
Biochem J. 1983 Aug 15;214(2):517-23. doi: 10.1042/bj2140517.
6
Mouse cytochrome P3-450: complete cDNA and amino acid sequence.小鼠细胞色素P3 - 450:完整的cDNA及氨基酸序列。
Nucleic Acids Res. 1984 Mar 26;12(6):2917-28. doi: 10.1093/nar/12.6.2917.
7
Identification of human cytochromes P-450 analogous to forms induced by phenobarbital and 3-methylcholanthrene in the rat.鉴定与大鼠中由苯巴比妥和3-甲基胆蒽诱导产生的形式类似的人细胞色素P-450。
Biochem J. 1985 Dec 15;232(3):869-76. doi: 10.1042/bj2320869.
8
Assignment of the human 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible cytochrome P1-450 gene to chromosome 15.人类2,3,7,8-四氯二苯并对二恶英诱导型细胞色素P1-450基因定位于15号染色体。
Nucleic Acids Res. 1985 Mar 25;13(6):2009-16. doi: 10.1093/nar/13.6.2009.
9
Isolation of human hepatic microsomes and their inhibition by cimetidine and ranitidine.
Eur J Clin Pharmacol. 1985;29(2):199-206. doi: 10.1007/BF00547422.
10
Liver mRNA probes disclose two cytochrome P-450 genes duplicated in tandem with the complement C4 loci of the mouse H-2S region.肝脏mRNA探针揭示了两个与小鼠H-2S区域的补体C4基因座串联重复的细胞色素P-450基因。
Proc Natl Acad Sci U S A. 1985 Jul;82(13):4453-7. doi: 10.1073/pnas.82.13.4453.