Burtsev E M, Miller L G, Gushchin A S, Shprakh V V, Savkov V S
Farmakol Toksikol. 1986 Sep-Oct;49(5):97-101.
Senzit increased volume velocity of the cerebral blood flow and oxygen delivery to the brain tissues under normal conditions at the expense of a decrease of the cerebral vessels tone. In transient cerebral ischemia the drug prevents disorders of cerebral circulation and a lowering of oxygen tension in the brain tissue. A prophylactic administration of senzit in carotid arterial occlusion prevents the development of edema and death of animals. Oral senzit produced an increase of blood supply to the brain and hypocoagulation changes in hemostasis system in patients with chronic insufficiency of cerebral circulation.
在正常情况下,Senzit通过降低脑血管张力来增加脑血流量和脑组织的氧气输送量。在短暂性脑缺血时,该药物可预防脑循环紊乱和脑组织中氧张力降低。在颈动脉闭塞时预防性给予Senzit可防止动物发生水肿和死亡。口服Senzit可增加脑循环慢性不足患者的脑供血,并使止血系统出现低凝变化。