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[优菲林和诺仕帕对脑血管阻力及脑缺血后动物存活率的影响]

[Effect of euphylline and no-shpa on cerebrovascular resistance and the survivability of animals after cerebral ischemia].

作者信息

Gaevyĭ M D, Ali A V

出版信息

Farmakol Toksikol. 1987 Mar-Apr;50(2):89-91.

PMID:3582642
Abstract

In acute experiments on anesthetized cats with total ischemia of the brain (15-minute arrest of blood autoperfusion of the cerebral vessels by a stable blood volume) it was shown that euphylline and no-shpa administered before ischemia or in the early period after ischemia inhibit or prevent the development of the postischemic phenomenon of non-recovery of the cerebral blood flow. The two drugs contributed to survival of albino rats following the brain ischemia produced by ligation of both carotid arteries.

摘要

在对麻醉猫进行的急性实验中,通过稳定血容量使脑血管自灌注血液完全停止造成脑缺血(15分钟),结果表明,在缺血前或缺血后早期给予氨茶碱和硝苯地平可抑制或预防脑血流缺血后无法恢复这一现象的发生。这两种药物有助于双侧颈总动脉结扎所致脑缺血的白化大鼠存活。

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Farmakol Toksikol. 1987 Mar-Apr;50(2):89-91.
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