Department of Psychology, San Diego State University, San Diego, California, USA.
Joint Doctoral Program in Clinical Psychology, San Diego State University/University of California, San Diego, San Diego, California, USA.
Int J Methods Psychiatr Res. 2023 Nov;32(S1):e1990. doi: 10.1002/mpr.1990. Epub 2023 Sep 13.
Rigorous validation of the full developmentally sensitive normal:abnormal spectrum, including evaluating the incremental value of age-specific behaviors, is necessary for nuanced characterization of dimensional features of psychopathology. To maximize the clinical utility of transdiagnostic approaches to risk identification, derivation of psychometrically sound, pragmatic versions with empirically derived cutoffs is also key. This special section has a central focus on rigorous, developmentally-based measurement of irritability as an exemplar of this theory- and pragmatically-based approach. Elevated irritability is a robust transdiagnostic predictor of the common psychopathologies of childhood. The Multidimensional Assessment Profiles Temper Loss (MAPS-TL) Scales are the only irritability tool specifically designed to capture the normal:abnormal dimensional spectrum. These have been extensively investigated in preschool age but lack rigorous modeling at older and younger ages. In this special issue, (with three independent-and one longitudinal-set of samples), we test and improve measurement of irritability as a transdiagnostic phenotype of psychopathology risk as it unfolds across development, expanding the MAPS-TL scale in three important ways: (1) extending irritability dimensional modeling and the developmental specification approach to older ages, (2) advancing science to practice translation by generating pragmatic irritability screening tools across ages, and (3) extending the dimensional, developmental specification approach to other dimensions of behavior, that is, internalizing. Collectively, the special issue operationalizes and advances application of a neurodevelopmental, dimensional and transdiagnostic approach to psychopathology.
异常谱，包括评估特定年龄行为的增量价值，对于细致刻画精神病理学的维度特征是必要的。为了最大限度地发挥跨诊断方法在风险识别方面的临床效用，推导出具有心理测量学稳健性和基于经验的临界值的实用版本也是关键。本特刊的核心重点是严格的、基于发展的易激惹测量，作为这种理论和实用方法的范例。易激惹是儿童常见精神病理学的一个强有力的跨诊断预测因子。多维评估概况脾气丧失（MAPS-TL）量表是唯一专门设计用于捕捉正常：异常维度谱的易激惹工具。这些量表在学龄前儿童中得到了广泛的研究，但在年龄较大和较小的儿童中缺乏严格的建模。在本特刊中（有三个独立的和一个纵向样本），我们测试并改进了易激惹作为精神病理学风险的跨诊断表型的测量，因为它在整个发展过程中展开，通过三种重要方式扩展了 MAPS-TL 量表：（1）将易激惹维度建模和发展规范方法扩展到较年长的年龄，（2）通过在不同年龄段生成实用的易激惹筛查工具，将科学转化为实践翻译，（3）将维度、发展规范方法扩展到其他行为维度，即内化。总的来说，特刊实现并推进了神经发育、维度和跨诊断方法在精神病理学中的应用。
