Laboratory of Experimental Rheumatology and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, Genoa, Italy.
IRCCS San Martino Polyclinic Hospital, Genoa, Italy.
Rheumatol Int. 2024 Feb;44(2):307-318. doi: 10.1007/s00296-023-05444-w. Epub 2023 Sep 13.
The engineered Hand Test System (HTS) glove has shown high reliability in assessing the baseline functional status of rheumatoid arthritis (RA) hand. Starting from this achievement, the aim of the present observational prospective study was to assess the functionality of the single fingers of rheumatoid hand at follow-up. Eighty RA patients performed HTS glove tests at baseline and among these fifty-six patients were re-tested after 7 months. The HTS glove parameters [Touch Duration (TD), Movement Rate (MR), Inter Tapping Interval (ITI)] were correlated with disease activity and disability clinimetric indexes [Disease Activity Score 28 joint count-C-reactive protein (DAS28-CRP), Clinical Disease Activity Index (CDAI), Simplified Disease Activity Index (SDAI), Health Assessment Questionnaire-Disability Index (HAQ-DI), grip strength, visual analogue scale of pain (VAS), patient global assessment (PGA)], and with laboratory values. HTS glove parameters (TD, ITI, and MR) showed statistically significant correlations with clinimetric and clinical indexes at both time points (p < 0.05). During follow-up, a statistically significant variation of all HTS glove parameters for the fingers that have performed both the worst or best HTS test at baseline was detected (p < 0.05), while the mean HTS glove parameter values by considering all fingers did not show a statistically significant variation over time, as well as the traditional clinimetric indexes. Besides the objective role in assessing the RA hand function by integrating the traditional clinimetric indexes, the HTS glove seems a useful tool for evaluating worst or best finger function during time by measuring the movement speed.
工程化的 Hand Test System (HTS) 手套在评估类风湿关节炎 (RA) 手部的基线功能状态方面表现出了高度的可靠性。基于这一成就，本观察性前瞻性研究旨在评估类风湿手部单个手指在随访时的功能。80 名 RA 患者在基线时进行了 HTS 手套测试，其中 56 名患者在 7 个月后进行了重复测试。HTS 手套参数 [触摸持续时间 (TD)、运动速度 (MR)、敲击间隔时间 (ITI)] 与疾病活动度和残疾临床计量学指标 [28 关节计数的疾病活动评分- C 反应蛋白 (DAS28-CRP)、临床疾病活动指数 (CDAI)、简化疾病活动指数 (SDAI)、健康评估问卷残疾指数 (HAQ-DI)、握力、疼痛视觉模拟评分 (VAS)、患者总体评估 (PGA)] 相关，并与实验室值相关。HTS 手套参数（TD、ITI 和 MR）在两个时间点均与临床计量学和临床指标呈统计学显著相关（p < 0.05）。在随访期间，检测到基线时 HTS 测试最差或最好的手指的所有 HTS 手套参数均有统计学显著变化（p < 0.05），而考虑所有手指的 HTS 手套参数平均值随时间没有显示出统计学显著变化，与传统的临床计量学指标一样。除了通过整合传统临床计量学指标来评估 RA 手部功能的客观作用外，HTS 手套似乎还是一种有用的工具，通过测量运动速度来评估时间内最差或最好手指的功能。
