Pandy G J
Med J Aust. 1979 Apr 7;1(7):264-6. doi: 10.5694/j.1326-5377.1979.tb112073.x.
Fifty-six patients with acute exacerbation of chronic bronchitis were given one week's treatment either with a combination of trimethoprim and sulphamethoxazole (TMP/SMX) or with doxycycline, in a single blind trial. The study found no significant difference in response to the two treatments, and confirmed that both TMP/SMX and doxycycline are effective and well tolerated agents, which are suitable for the management of acute or chronic bronchitis.
在一项单盲试验中，对56例慢性支气管炎急性加重患者进行了为期一周的治疗，分别给予甲氧苄啶和磺胺甲恶唑联合制剂（TMP/SMX）或强力霉素治疗。研究发现，两种治疗的反应没有显著差异，并证实TMP/SMX和强力霉素都是有效的且耐受性良好的药物，适用于急性或慢性支气管炎的治疗。
