Department of Thyroid and Breast Surgery, Xian Daxing Hospital, Xian, 0710000, China.
Xi'an Railway Technician Institute, Xian, 0710000, China.
Asian J Surg. 2024 Jan;47(1):350-353. doi: 10.1016/j.asjsur.2023.08.218. Epub 2023 Sep 12.
This study aims to evaluate the feasibility and safety of percutaneous radiofrequency ablation guided by ultrasound for treating papillary thyroid microcarcinoma.
At our institution, fifty people who had been treated for micropapillary thyroid cancer with ultrasound-guided radiofrequency ablation were chosen. Thyroid function was evaluated after one month, and the volume of the ablation region was assessed immediately, 3, 6, and 12 months after treatment. At the same time, the complications or adverse reactions after treatment were evaluated.
As time passed, the volume of the ablation area decreased gradually, showing a regression trend. There was a significant difference in the volume of the ablation area between adjacent groups (P < 0.05), and the tumor volume reduction ratio (VRR) of the ablation area was a statistically significant difference between adjacent groups (P < 0.05). There was no significant difference between the indexes related to thyroid function before and after treatment(P > 0.05). No local recurrence or distant metastasis was found during follow-up; The most common complication after the operation was a slight pain in the neck. A few patients had toothache and neck swelling symptoms, and the above symptoms subsided within 24 h after the operation.
Ultrasound-guided radiofrequency ablation is safe and effective for treating single-focus micropapillary thyroid carcinoma while retaining thyroid function, with few and minor complications, which can be used as an ideal surgical option.
本研究旨在评估超声引导经皮射频消融治疗甲状腺微小乳头状癌的可行性和安全性。
在我院,选择了 50 名经超声引导射频消融治疗微乳头状甲状腺癌的患者。治疗后 1 个月评估甲状腺功能,治疗后即刻、3、6、12 个月评估消融区域的体积。同时评估治疗后并发症或不良反应。
随着时间的推移,消融区域的体积逐渐减少,呈消退趋势。相邻组间消融区域体积差异有统计学意义(P<0.05),相邻组间消融区域肿瘤体积缩小率(VRR)差异有统计学意义(P<0.05)。治疗前后甲状腺功能相关指标差异无统计学意义(P>0.05)。随访期间未发现局部复发或远处转移;术后最常见的并发症是轻微颈部疼痛。少数患者有牙痛和颈部肿胀症状,上述症状在术后 24 小时内缓解。
超声引导射频消融治疗单灶性微小乳头状甲状腺癌保留甲状腺功能安全有效,并发症少且轻微,可作为一种理想的手术选择。