Emerg Infect Dis. 2023 Nov;29(11):2380-2382. doi: 10.3201/eid2911.230836. Epub 2023 Sep 13.
We conducted surveillance of respiratory syncytial virus (RSV) genomic sequences for 100 RSV-A and 27 RSV-B specimens collected during November 2022-April 2023 in Arizona, USA. We identified mutations within prefusion F-protein antigenic sites in both subtypes. Continued genomic surveillance will be critical to ensure RSV vaccine effectiveness.
我们对 2022 年 11 月至 2023 年 4 月在美国亚利桑那州采集的 100 份 RSV-A 和 27 份 RSV-B 样本进行了呼吸道合胞病毒(RSV)基因组序列监测。我们在两种亚型的融合前 F 蛋白抗原位点都发现了突变。持续的基因组监测对于确保 RSV 疫苗的有效性至关重要。