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评估姑息治疗对临终癌症成年患者入院治疗的影响。

Assessing the impact of palliative care admission of end-of-life cancer adults.

作者信息

Díez-Concha Jose F, Gómez-García Diego Mauricio, Agudelo Julián Alberto, Lizarazo Herrera Edwin Alexander

机构信息

Faculty of Health, Department of Family Medicine, Universidad del Valle, Cra 119a #60b-75, Cali, Valle del Cauca 760035, Colombia.

Faculty of Health, Department of Family Medicine, Universidad del Valle, Calle 15a #69-85, Cali, Valle del Cauca 760033, Colombia.

出版信息

Palliat Care Soc Pract. 2023 Sep 11;17:26323524231198545. doi: 10.1177/26323524231198545. eCollection 2023.

Abstract

BACKGROUND

There is evidence that early admission to the palliative care (PC) program in adult cancer patients improves symptoms management, reduces unplanned hospital admissions, minimizes aggressive cancer treatments, and enables patients to make decisions about their end-of-life (EOL) care.

OBJECTIVES

This retrospective cohort study aimed to determine whether late admission to a PC program is associated with aggressive treatment at the EOL in adult patients with oncological diseases from their admission until death.

DESIGN/METHODS: The study evaluated the aggressiveness in EOL management in patients with advanced stage oncological diseases who died between 2017 and 2019. The study population was divided into two groups based on the time of admission to the PC program. Aggressiveness at the EOL was measured using five criteria: treatment, hospital admission and duration, emergency department care, and/or intensive care unit utilization.

RESULTS

The study found a significant difference in the rate of aggressive EOL treatments between late admission to PC care and early admission [adjusted EOL 79.6% 70.4%; relative risk (RR): 1.98, 90% CI: 1.08-3.59, : 0.061]; In the analysis of secondary variables, a significant association was observed between early admission to PC and the suspension of active treatments at the EOL, leading to a decrease in aggressiveness (77% 55.8%; RR: 1.38, 95% CI: 1.14-1.67, : 0.004).

CONCLUSION

Our findings suggest that early referral to PC services is associated with less aggressive treatment at the EOL, including suspension of active treatments.

摘要

背景

有证据表明,成年癌症患者早期进入姑息治疗(PC)项目可改善症状管理、减少非计划住院、尽量减少积极的癌症治疗,并使患者能够就其临终(EOL)护理做出决定。

目的

这项回顾性队列研究旨在确定晚期进入PC项目是否与成年肿瘤疾病患者从入院到死亡期间临终时的积极治疗相关。

设计/方法:该研究评估了2017年至2019年间死亡的晚期肿瘤疾病患者临终管理的积极程度。根据进入PC项目的时间将研究人群分为两组。使用五个标准衡量临终时的积极程度:治疗、住院及住院时长、急诊科护理和/或重症监护病房的使用情况。

结果

研究发现,晚期接受PC护理与早期接受PC护理的患者在积极的临终治疗率上存在显著差异[调整后的临终治疗率分别为79.6%和70.4%;相对风险(RR):1.98,90%置信区间(CI):1.08 - 3.59,P = 0.061];在对次要变量的分析中,观察到早期进入PC与临终时停止积极治疗之间存在显著关联,导致积极程度降低(分别为77%和55.8%;RR:1.38,95%CI:1.14 - 1.67,P = 0.004)。

结论

我们的研究结果表明,早期转诊至PC服务与临终时较少的积极治疗相关,包括停止积极治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e493/10496487/fef2a6aaf116/10.1177_26323524231198545-fig1.jpg

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