Hlinák Z
Horm Behav. 1986 Sep;20(3):263-9. doi: 10.1016/0018-506x(86)90036-x.
The copulatory and precopulatory behavioral repertoire expressed in terms of the intensity scale of sexual responsiveness was investigated in female rats ovariectomized on the 30th day after birth and treated for 9 weeks, once weekly, with estradiol dipropionate (5, 10, 15, 20, and 30 micrograms per animal) plus progesterone (in the range from 0.0 to 2.4 mg per animal). It was found that the higher the dosage of estradiol and progesterone used, the more complete the precopulatory behavioral pattern that was induced. Further, the same level of sexual responsiveness was achieved by various combinations of both hormones used. The dose-response relationships are less complicated in prepubertally ovariectomized females in comparison with those spayed as adults. Finally, the most complete pattern, characterized by ritualized darting, was not achieved at all.
对出生后第30天进行卵巢切除的雌性大鼠进行了研究，这些大鼠每周接受一次己酸雌二醇（每只动物5、10、15、20和30微克）加孕酮（每只动物0.0至2.4毫克）的治疗，为期9周，研究了以性反应强度量表表示的交配和交配前行为表现。结果发现，使用的雌二醇和孕酮剂量越高，诱导的交配前行为模式就越完整。此外，两种激素的不同组合也能达到相同水平的性反应。与成年后进行卵巢切除的雌性大鼠相比，青春期前进行卵巢切除的雌性大鼠的剂量反应关系不那么复杂。最后，以仪式化飞奔为特征的最完整模式根本没有实现。
