Merkx J, Slob A K, van der Werff ten Bosch J J
Department of Endocrinology, Growth and Reproduction, Faculty of Medicine, Erasmus University, Rotterdam, The Netherlands.
Physiol Behav. 1987;40(6):737-40. doi: 10.1016/0031-9384(87)90276-9.
From the present study it appears that castrated male rats can be made attractive to intact males by estradiol benzoate plus progesterone (EB + P). For the determination of attractivity a residential plus-maze was used in which the resident male could choose between the company of the experimental male and that of an ovariectomized female with or without EB + P. In one experiment the males were castrated in adulthood; these animals were less attractive than the ovariectomized females with a similar hormone treatment. In a second experiment it was found that males that had been castrated at birth were as attractive as the ovariectomized females, after treatment with EB + P. These findings indicate that the attractivity that can be induced by EP + P in gonadectomized adult rats is somewhat but not wholly reduced if androgen is present during the neonatal period.
从目前的研究来看，似乎去势雄鼠可以通过苯甲酸雌二醇加孕酮（EB + P）变得对未去势雄鼠有吸引力。为了确定吸引力，使用了一个居住型十字迷宫，在其中，常住雄鼠可以在实验雄鼠以及接受或未接受EB + P处理的去卵巢雌鼠的陪伴之间做出选择。在一项实验中，雄鼠在成年期被去势；这些动物比接受类似激素处理的去卵巢雌鼠吸引力小。在第二项实验中发现，出生时即被去势的雄鼠在接受EB + P处理后与去卵巢雌鼠一样有吸引力。这些发现表明，如果在新生期存在雄激素，那么在成年去性腺大鼠中由EP + P诱导的吸引力会有所降低，但不会完全消失。
