Rheumatology Department, National Institute of Cardiology, Mexico City, Mexico.
Clin Rheumatol. 2023 Nov;42(11):3167-3171. doi: 10.1007/s10067-023-06743-0. Epub 2023 Sep 14.
There is a clear clinical overlap between fibromyalgia, myalgic encephalomyelitis, and post-COVID 19 condition. Chronic fatigue, cognitive impairment, and widespread pain characterize these 3 syndromes. A steady line of investigation posits fibromyalgia as stress-evoked sympathetically maintained neuropathic pain syndrome and places dorsal root ganglia dysregulation with the ensuing small fiber neuropathy at the epicenter of fibromyalgia pathogenesis. This article discusses emerging evidence suggesting that similar mechanism may operate in post-COVID 19 condition.
纤维肌痛、慢性疲劳综合征和新冠后综合征之间存在明显的临床重叠。这三种综合征的特征是慢性疲劳、认知障碍和广泛疼痛。一系列研究表明纤维肌痛是由应激引起的交感神经维持的神经性疼痛综合征，并将背根神经节失调和随之而来的小纤维神经病置于纤维肌痛发病机制的中心。本文讨论了一些新出现的证据，表明类似的机制可能也存在于新冠后综合征中。
