Risberg Jan, van Ooij Pieter-Jan, Matity Lyubisa
NUI, Bergen, Norway.
Diving Medical Center; Royal Netherlands Navy, Den Helder, The Netherlands.
Undersea Hyperb Med. 2023 Third Quarter;50(3):301-306.
A recent review suggested that the measure K = t² x pO₂ [4.57] (t is exposure time in h, pO in atm) should replace unit pulmonary toxic dose (UPTD) as an exposure index for pulmonary oxygen toxicity (POT) in surface-oriented diving. K would better predict reduction in vital capacity (VC) during exposure and allow prediction of recovery. Although K is more accurate estimating VC changes than UPTD, the calculation of K is more extensive, particularly when estimating hyperoxic exposure for dives with multiple pO₂ segments. Furthermore, and in contrast with UPTD, K is difficult to interpret on its own given its non- linear dimension of time. We suggest that a new metric: ESOT (equivalent surface oxygen time) should be used to replace UPTD. ESOT = t x pO₂ [2.285] (t is exposure time in minutes, pO in atm). ESOT=1 is thus the hyperoxic exposure reached after one minute of breathing 100% O₂ at surface pressure. Hyperoxic monitoring by ESOT is more practical than K to apply in an operational environment, with no loss of accuracy in POT prediction. In addition, it intuitively allows interpreting hyperoxic exposures on its own, analogous to UPTD. The daily hyperoxic threshold limits suggested by Risberg and van Ooij for two, five and an unlimited number of successive diving days would translate to ESOTs of 650, 500 and 420 respectively.
最近的一项综述表明,测量值K = t² × pO₂ [4.57](t为暴露时间,单位为小时,pO为大气压)应取代单位肺毒性剂量(UPTD),作为水面定向潜水时肺氧中毒(POT)的暴露指数。K能更好地预测暴露期间肺活量(VC)的降低情况,并能预测恢复情况。尽管K在估算VC变化方面比UPTD更准确,但K的计算更为复杂,尤其是在估算具有多个pO₂段的潜水的高氧暴露时。此外,与UPTD不同,鉴于K的时间维度是非线性的,其本身难以解释。我们建议应使用一种新的指标:等效水面氧时间(ESOT)来取代UPTD。ESOT = t × pO₂ [2.285](t为暴露时间,单位为分钟,pO为大气压)。因此,ESOT = 1是在水面压力下呼吸100%氧气一分钟后达到的高氧暴露。在操作环境中,通过ESOT进行高氧监测比K更实用,在POT预测中不会损失准确性。此外,它直观地允许单独解释高氧暴露情况,类似于UPTD。里斯伯格和范·奥伊伊针对连续两天、五天和无限制天数提出的每日高氧阈值限制分别对应于ESOT值650、500和420。