Landahl S, Bengtsson C, Sigurdsson J A, Svanborg A, Svärdsudd K
Hypertension. 1986 Nov;8(11):1044-9. doi: 10.1161/01.hyp.8.11.1044.
This report is based on three different representative population samples of a total of 1304 men (50-79 years old) and 1246 women (38-79 years old) observed for up to 12 years. Subjects' consumption of antihypertensive drugs and blood pressure levels in subjects with and without such treatment are presented. The prevalence of treatment with antihypertensive drugs (including beta-blockers and diuretics for other indications) increased from 2% at age 50 years to 37% at 79 years of age among the men and from 1% at 38 years to 61% at 79 years of age among the women. The mean systolic/diastolic blood pressure in untreated subjects increased from 138/91 mm Hg at age 50 years to 159/91 mm Hg at age 70 years in the men and from 123/79 mm Hg at age 38 years to 168/93 mm Hg at age 70 years in the women. At age 79 years the mean systolic/diastolic blood pressure was 155/83 mm Hg in the men and 161/85 mm Hg in the women. In a longitudinal follow-up of reexamined subjects, there was an increase in systolic blood pressure levels up to age 75 years and a reduction in diastolic blood pressure after age 75 years in both sexes.
本报告基于三个不同的代表性人群样本，共观察了1304名男性（50 - 79岁）和1246名女性（38 - 79岁），观察时间长达12年。报告呈现了受试者使用抗高血压药物的情况以及接受和未接受此类治疗的受试者的血压水平。男性中，使用抗高血压药物（包括用于其他适应症的β受体阻滞剂和利尿剂）的患病率从50岁时的2%上升至79岁时的37%；女性中，该患病率从38岁时的1%上升至79岁时的61%。未接受治疗的受试者的平均收缩压/舒张压，男性从50岁时的138/91毫米汞柱升至70岁时的159/91毫米汞柱，女性从38岁时的123/79毫米汞柱升至70岁时的168/93毫米汞柱。在79岁时，男性的平均收缩压/舒张压为155/83毫米汞柱，女性为161/85毫米汞柱。在对重新检查的受试者进行的纵向随访中，两性的收缩压水平在75岁之前均有所上升，而在75岁之后舒张压则有所下降。
