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原发性反肩关节置换术中感染痤疮丙酸杆菌的患者的功能结果和并发症:两年和五年随访研究。

Functional outcomes and complications of patients contaminated with Cutibacterium acnes during primary reverse shoulder arthroplasty: study at two- and five-years of follow-up.

机构信息

Department of Orthopedics, Hospital del Mar, Parc de Salut Mar, Passeig Marítim 25-29, 08003, Barcelona, Spain.

Department of Orthopedics, Sant Joan de Déu Hospital Palma Inca, Palma, Mallorca, Spain.

出版信息

Int Orthop. 2023 Nov;47(11):2827-2833. doi: 10.1007/s00264-023-05971-y. Epub 2023 Sep 15.

DOI:10.1007/s00264-023-05971-y
PMID:37710071
Abstract

PURPOSE

The objective of the study was to compare the functional outcomes and the complication rate of the patients with C. acnes contamination at the end of the primary reverse shoulder arthroplasty (RSA) surgery to those patients without C. acnes contamination.

METHOD

A total of 162 patients were included. In all cases, skin and deep tissue cultures were obtained. A molecular typing characterization of the C. acnes strains was performed. Functional outcomes were assessed with the Constant score at the two and five year follow-up and all complications were also recorded.

RESULTS

A total of 1380 cultures were obtained from the 162 primary RSA surgeries. Of those, 96 turned out to be positive for C. acnes. There were 25 patients with positive cultures for C. acnes. The overall postoperative Constant score was not significantly different between those patients having C. acnes-positive cultures and those with negative cultures at the two and five year follow-up (59.2 vs. 59.6 at two years, p 0.870, and 59.5 vs. 62.4 at five years, p 0.360). Patients with positive cultures presented a higher complication rate (p 0.001) with two infections, one revision surgery, and one dislocation.

CONCLUSION

Patients ending up with C. acnes-positive cultures after primary shoulder arthroplasty surgery do not have worse clinical outcomes when compared to patients having negative cultures, but a greater number of complications were found in those patients with C. acnes-positive cultures.

摘要

目的

本研究旨在比较原发性反肩关节置换术(RSA)术后末端痤疮丙酸杆菌(C. acnes)污染患者与无 C. acnes 污染患者的功能结果和并发症发生率。

方法

共纳入 162 例患者。所有病例均获取皮肤和深部组织培养物。对 C. acnes 菌株进行分子分型特征分析。采用 Constant 评分评估功能结果,并在两年和五年随访时进行评估,同时记录所有并发症。

结果

从 162 例原发性 RSA 手术中获得了 1380 份培养物。其中 96 份培养物为 C. acnes 阳性。25 例患者的 C. acnes 培养物呈阳性。在两年和五年随访时,C. acnes 培养物阳性患者的术后总 Constant 评分与培养物阴性患者无显著差异(两年时为 59.2 比 59.6,p 0.870,五年时为 59.5 比 62.4,p 0.360)。阳性培养物患者的并发症发生率较高(p 0.001),包括 2 例感染、1 例翻修手术和 1 例脱位。

结论

与培养物阴性患者相比,原发性肩部关节置换术后末端 C. acnes 培养物阳性的患者临床结果并无恶化,但 C. acnes 培养物阳性患者的并发症发生率更高。

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Eur J Clin Microbiol Infect Dis. 2022 Jan;41(1):169-173. doi: 10.1007/s10096-021-04348-6. Epub 2021 Sep 17.
2
Incidence of in open shoulder surgery.开放性肩部手术中的[具体病症]发生率。
Nagoya J Med Sci. 2021 Feb;83(1):151-157. doi: 10.18999/nagjms.83.1.151.
3
Unexpected positive cultures after revision shoulder arthroplasty: does it affect outcome?
翻修肩关节置换术后意外的阳性培养:是否会影响结果?
J Shoulder Elbow Surg. 2021 Jun;30(6):1299-1308. doi: 10.1016/j.jse.2020.12.014. Epub 2021 Feb 3.
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What is the clinical impact of positive cultures at the time of primary total shoulder arthroplasty?初次全肩关节置换时阳性培养物的临床影响是什么?
J Shoulder Elbow Surg. 2021 Jun;30(6):1324-1328. doi: 10.1016/j.jse.2020.08.032. Epub 2020 Sep 10.
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Cutibacterium acnes is an intracellular and intra-articular commensal of the human shoulder joint.痤疮丙酸杆菌是人类肩关节的细胞内和关节内共生菌。
J Shoulder Elbow Surg. 2021 Jan;30(1):16-26. doi: 10.1016/j.jse.2020.04.020. Epub 2020 Jun 9.
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Cutibacterium subtype distribution on the skin of primary and revision shoulder arthroplasty patients.原发性和翻修肩关节置换术后患者皮肤的表皮葡萄球菌亚型分布。
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