Cloned fragments of the plasmid ColV,I-K94 specifying virulence and serum resistance.
作者信息
Binns M M, Davies D L, Hardy K G
出版信息
Nature. 1979 Jun 28;279(5716):778-81. doi: 10.1038/279778a0.
DOI:10.1038/279778a0
PMID:377103
Abstract
A cloned BamH1-generated fragment of ColV,I-K94 increased the virulence of Escherichia coli, causing an approximately 100-fold reduction in LD50 for chicks. A genetic determinant for resistance to the bactericidal effects of serum was mapped to a 5,300 base-pair sequence within the fragment. Neither colicin V nor immunity to colicin V affected the pathogenicity of E. coli for chicks.
摘要
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