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卵巢血吸虫病:血吸虫被忽视的异位侵犯的挑战。病例报告及文献复习。

Ovarian schistosomiasis: challenges of a neglected ectopic involvement of blood flukes. Case report and review of literature.

机构信息

Department of Pathology, Catholic University of Health and Allied Sciences-Bugando, Tanzania.

Consolata Hospital, Ikonda, Njombe, Tanzania.

出版信息

Pathologica. 2023 Aug;115(4):237-245. doi: 10.32074/1591-951X-891.

Abstract

INTRODUCTION

Female genital schistosomiasis (FGS), infection of . trematode in the gynaecological apparatus, is the most neglected sexual and reproductive health condition in sub-Saharan Africa with an estimated of 20-120 million cases. The ectopic entrapment of eggs after oviposition can occur in 0.5% of cases in fallopian tubes and ovaries.

THE CASE

We report a case of 38-years-old woman assessed for a 10 year history of infertility. On ultrasound, multiple cystic formations were observed in the ovary. Histology after oophorectomy to exclude malignancy showed granulomatous formations surrounding . eggs in proximity of corpus luteus and haemorragicum.

DISCUSSION

Ectopic Schistosome oviposition, seen in the ovary and fallopian tubes as in our case, can be a potential cause of reproductive organ damage and complications such as infertility, ectopic pregnancy, miscarriage, premature birth, low birth weight, and even maternal death.

CONCLUSIONS

More studies are needed on ovarian FGS and its impact on women fertility to guide specific interventions targeting vulnerable population of childbearing age, contributing to the NTD WHO 2030 aim of eliminating schistosomiasis as a matter of public health.

摘要

简介

女性生殖器血吸虫病(FGS)是一种 吸虫在妇科器官的感染,是撒哈拉以南非洲地区被忽视的最严重的性健康和生殖健康问题之一,估计有 2000 万至 1.2 亿病例。产卵后 虫卵的异位滞留可能在输卵管和卵巢的 0.5%的病例中发生。

病例

我们报告了一位 38 岁妇女的病例,她因 10 年不孕病史就诊。超声检查发现卵巢有多囊性形成。为排除恶性肿瘤而进行的卵巢切除术后的组织学检查显示,在黄体和血肿附近有 虫卵周围有肉芽肿形成。

讨论

如我们的病例所示, 卵在卵巢和输卵管中的异位产卵可能是生殖器官损伤和并发症的潜在原因,如不孕、异位妊娠、流产、早产、低出生体重,甚至产妇死亡。

结论

需要对卵巢 FGS 及其对女性生育能力的影响进行更多研究,以指导针对生育年龄脆弱人群的具体干预措施,为世卫组织 2030 年消除血吸虫病作为公共卫生问题的目标做出贡献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4d0/10688251/d053b81aef5e/pathol-2023-04-237-g001.jpg

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