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医用胶与传统缝合治疗儿童颌面部负压封闭引流后犬咬伤的临床效果分析：一项随机试验。

Clinical effect analysis of using medical glue versus conventional suturing to treat dog bite in children's maxillofacial region after negative pressure sealing drainage: A randomized trial.

机构信息

Aerospace Center Hospital, Beijing, China.

出版信息

Medicine (Baltimore). 2023 Sep 15;102(37):e34837. doi: 10.1097/MD.0000000000034837.

DOI:10.1097/MD.0000000000034837
PMID:37713853
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10508562/
Abstract

BACKGROUND

To compare the clinical effectiveness of applying medical glue versus conventional suturing after primary suturing and continuous vacuum sealing drainage (VSD) technology in the treatment of facial wounds caused by dog bites in children's maxillofacial region, with respect to operation time, wound infection rate, treatment effect, and patient satisfaction.

METHODS

From May 2020 to July 2022, 68 children with a dog bite in the maxillofacial region were randomly divided into medical glue and conventional suturing groups. The patients in both groups were treated with conventional debridement, tetanus and/or rabies immunization, and antibiotic therapy. The medical glue group was treated with VSD after the first-stage of the loose suture of the wound. After 5 days, the suture was removed, and the wound was tightly bonded with medical glue again. The conventional suturing group was treated with VSD after the first-stage of loose suture of the wound. The primary outcomes were the operation time and satisfaction of the 2 groups, and the secondary outcomes was the wound infection rate.

RESULTS

The operation time of the medical glue group was significantly lower than that of the conventional suturing group. However, there was no significant difference between the 2 groups in the wound infection rate. Still, the patient satisfaction was significantly better in the medical glue group than the conventional suturing group with statistically significant difference (P < .05).

CONCLUSION

In conclusion, applying medical glue after using negative pressure sealing drainage in treating maxillofacial dog bites can reduce surgeons work intensity, lessen children's pain, and improve the clinical treatment effect.

摘要

背景

比较在儿童颌面犬咬伤中，初次缝合后应用医用胶与传统缝合加持续负压封闭引流（VSD）技术治疗的临床效果，包括手术时间、伤口感染率、治疗效果和患者满意度。

方法

2020 年 5 月至 2022 年 7 月，将 68 例颌面犬咬伤患儿随机分为医用胶组和传统缝合组。两组患者均给予常规清创、破伤风和/或狂犬病免疫接种及抗生素治疗。医用胶组采用 VSD 处理一期松缝伤口，5 天后拆除缝线，再次使用医用胶紧密贴合伤口。传统缝合组采用 VSD 处理一期松缝伤口。主要结局为两组的手术时间和满意度，次要结局为伤口感染率。

结果

医用胶组的手术时间明显低于传统缝合组，但两组的伤口感染率无显著差异。然而，医用胶组的患者满意度明显高于传统缝合组，差异有统计学意义（P ＜.05）。

结论

总之，负压封闭引流后应用医用胶治疗颌面犬咬伤可减轻手术医生的工作强度，减轻患儿的痛苦，提高临床治疗效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32fd/10508562/9d003c308655/medi-102-e34837-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32fd/10508562/d668c6a54787/medi-102-e34837-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32fd/10508562/e6f6975c3929/medi-102-e34837-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32fd/10508562/96dac1c59442/medi-102-e34837-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32fd/10508562/d09091c22898/medi-102-e34837-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32fd/10508562/4e7ed0dfb7da/medi-102-e34837-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32fd/10508562/9d003c308655/medi-102-e34837-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32fd/10508562/d668c6a54787/medi-102-e34837-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32fd/10508562/e6f6975c3929/medi-102-e34837-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32fd/10508562/96dac1c59442/medi-102-e34837-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32fd/10508562/d09091c22898/medi-102-e34837-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32fd/10508562/4e7ed0dfb7da/medi-102-e34837-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32fd/10508562/9d003c308655/medi-102-e34837-g006.jpg

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本文引用的文献

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J Public Health Res. 2021 Apr 13;10(3):2168. doi: 10.4081/jphr.2021.2168.
2
Tissue Adhesives: From Research to Clinical Translation.组织黏合剂：从研究到临床转化
Nano Today. 2021 Feb;36. doi: 10.1016/j.nantod.2020.101049. Epub 2020 Dec 20.
3
Pet dog bites in children: management and prevention.儿童宠物狗咬伤：处理与预防
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J Clin Med. 2023 Nov 6;12(21):6942. doi: 10.3390/jcm12216942.
BMJ Paediatr Open. 2020 Aug 11;4(1):e000726. doi: 10.1136/bmjpo-2020-000726. eCollection 2020.
4
Dog Bite Wound: A Dilemma into the Immediate Surgical Approach.犬咬伤伤口：即刻手术入路的难题
Indian J Plast Surg. 2020 Mar;53(1):159-161. doi: 10.1055/s-0040-1709914. Epub 2020 Apr 17.
5
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Front Psychol. 2019 Dec 11;10:2775. doi: 10.3389/fpsyg.2019.02775. eCollection 2019.
6
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7
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