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如何预测原发性脑干出血的预后:一项单中心回顾性分析的 6 年结果。

How to predict the outcome of primary brainstem hemorrhage: Six-year results of a single-center retrospective analysis.

机构信息

Department of Neurosurgery, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.

Department of Emergency Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.

出版信息

Medicine (Baltimore). 2023 Sep 15;102(37):e35131. doi: 10.1097/MD.0000000000035131.

Abstract

Primary brainstem hemorrhage (PBH) is one of the most fatal intracranial hemorrhages, evaluating the prognosis in the early stage is vital for appropriate therapeutic planning. Our study aimed to identify risk factors for 30-day mortality and 90-day functional recovery of PBH. Data from 63 patients with PBH admitted to Beijing Chaoyang Hospital between 2016 and 2022 were retrieved for this study. We grouped the patients according to 30-day survival or 90-day functional recovery. Independent risk factors of 30-day mortality and 90-day functional recovery were identified by univariate and multivariate logistic regression analyses. 31 patients (49.2%) died within 30 days and 22 patients (34.9%) achieved better functional recovery. By multivariate analysis, Glasgow coma scale <9 on admission and tachycardia were significantly associated with 30-day mortality, while the hematoma volume >5 mL was an independent risk factor for 90-day functional recovery. Initial level of consciousness, tachycardia, massive hematoma were risk factors for prognosis, which must be seriously evaluated for therapeutic planning.

摘要

原发性脑干出血(PBH)是颅内出血中最致命的一种,早期评估预后对于制定适当的治疗计划至关重要。本研究旨在确定 PBH 患者 30 天死亡率和 90 天功能恢复的危险因素。本研究回顾性分析了 2016 年至 2022 年期间在北京朝阳医院住院的 63 例 PBH 患者的数据。我们根据 30 天内的生存或 90 天内的功能恢复对患者进行分组。采用单因素和多因素逻辑回归分析确定 30 天死亡率和 90 天功能恢复的独立危险因素。31 例(49.2%)患者在 30 天内死亡,22 例(34.9%)患者功能恢复较好。多因素分析显示,入院时格拉斯哥昏迷量表评分<9 和心动过速与 30 天死亡率显著相关,而血肿量>5ml 是 90 天功能恢复的独立危险因素。意识初始水平、心动过速、大量血肿是预后的危险因素,在制定治疗计划时必须认真评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b68/10508365/436879caff81/medi-102-e35131-g001.jpg

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