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预防围手术期环境中的管制药物转移:一篇叙述性综述。

Preventing controlled substance diversion in perioperative settings: a narrative review.

作者信息

Wong Michael J, Wang Yongjun, Blake Lindsay, Ke Janny X C

机构信息

Department of Anesthesia, Pain Management & Perioperative Medicine, Dalhousie University, Saint John, NB, Canada.

Department of Anesthesiology, Perioperative and Pain Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.

出版信息

Can J Anaesth. 2023 Dec;70(12):1989-2001. doi: 10.1007/s12630-023-02574-4. Epub 2023 Sep 15.

Abstract

PURPOSE

Diversion of controlled substances in the perioperative setting is an ongoing challenge, with consequences for patients, anesthesiologists, perioperative staff, and health care facilities alike. Perioperative environments are at high risk for diversion, since controlled substances are frequently handled in these settings, with varying levels of oversight. In this narrative review, we summarize strategies for preventing diversion of controlled substances in perioperative settings (i.e., operating rooms, endoscopy suites, and postanesthesia recovery units).

SOURCE

We performed a targeted literature search in PubMed MEDLINE, Embase, Scopus, Web of Science, the Cochrane Register of Controlled trials, and the Cochrane Database of Systematic Reviews, as well as a manual search for additional references. We used terminology related to drug diversion, drug abuse, anesthesiologists, pharmacists, physicians, operating room personnel, and controlled substances.

PRINCIPAL FINDINGS

Many strategies have been described for preventing diversion in perioperative settings, and these are broadly categorized into: education, distribution, auditing, or provider screening. Some of these approaches may be time- and resource-intensive. There is limited evidence to inform anesthesia departments' choice of which strategies to adopt.

CONCLUSION

Although awareness of perioperative controlled substance diversion has been improving, there are too few data to suggest an optimal approach. Anesthesia departments will need to work collaboratively with hospital pharmacies and actively select strategies that are reasonable given local resources.

摘要

目的

围手术期环境中管制药品的转移是一个持续存在的挑战,会给患者、麻醉医生、围手术期工作人员以及医疗保健机构带来不良后果。围手术期环境存在很高的药品转移风险,因为管制药品在这些环境中经常被使用,且监管程度各不相同。在这篇叙述性综述中,我们总结了围手术期环境(即手术室、内镜检查室和麻醉后恢复室)中防止管制药品转移的策略。

来源

我们在PubMed MEDLINE、Embase、Scopus、Web of Science、Cochrane对照试验注册库和Cochrane系统评价数据库中进行了针对性的文献检索,并手动搜索了其他参考文献。我们使用了与药品转移、药物滥用、麻醉医生、药剂师、医生、手术室人员和管制药品相关的术语。

主要发现

已经描述了许多围手术期防止药品转移的策略,这些策略大致可分为:教育、分发、审计或对提供者进行筛查。其中一些方法可能耗费时间和资源。关于麻醉科应采用何种策略的选择,可供参考的证据有限。

结论

尽管对围手术期管制药品转移的认识一直在提高,但数据太少,无法表明最佳方法。麻醉科需要与医院药房合作,并根据当地资源积极选择合理的策略。

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