Department of Pharmacy, The Affiliated Hospital of Qingdao University, Shandong, Qingdao, China.
Adv Ther. 2024 May;41(5):1953-1966. doi: 10.1007/s12325-024-02814-z. Epub 2024 Mar 18.
In alignment with China's national directive for improved drug management in anesthesiology, the Affiliated Hospital of Qingdao University initiated a quality improvement project, aiming to tackle the prevailing challenges of inefficiencies in drug administration, escalating drug costs, and the notable communication gap between pharmacists and anesthesiologists.
We employed a Plan-Do-Study-Act methodology to establish a pharmacy team and execute a multidimensional pharmaceutical intervention. The interventions included the formulation of standard procedures, guidelines and regulations, assistance from an information system (including automatic dispensing cabinets and prospective prescription review system), communication feedback (via WeChat groups), and education for anesthesiology staff. The intervention spanned from April to September 2023, focusing on optimizing medication management, achieving cost savings, and enhancing the satisfaction of anesthesia team members, with an additional observation from October to December 2023.
Following the interventions, improvements were observed in drug management practices. These enhancements included increased compliance with accounting procedures, more rigorous registration of controlled substances, and more effective disposal of liquid residues. There was no adverse events related to high-alert medications or look-alike drug usage errors. The introduction of automatic dispensing cabinets and a prospective prescription review system markedly improved work efficiency. The utilization of a WeChat group facilitated effective communication about unreasonable prescriptions and drug-related issues. Among the 29,061 patients who underwent surgery both before and after the interventions, significant reductions were observed both in the drug proportion and the per capita drug costs (P = 0.03, P = 0.014, respectively). The per capita drug cost decreased by 20.82%, from ¥723.43 to ¥572.78, consistently remaining below ¥600 throughout the 9-month observation period. The per capita cost of monitoring drugs including dezocine, butorphanol, haemocoagulase agkistrodon, penehyclidine, and ulinastatin experienced a significant reduction (P < 0.05). Additionally, in the satisfaction questionnaires returned, a remarkable 94.44% of anesthesiology staff expressed high satisfaction with the comprehensive pharmaceutical interventions.
The quality improvement project has yielded remarkable positive outcomes, serving as a model worthy of reference and replication in similar healthcare settings.
为响应中国国家改善麻醉学药物管理的指令,青岛大学附属医院启动了一项质量改进项目,旨在解决药物管理效率低下、药物成本不断上升以及药师与麻醉师之间明显沟通不畅等问题。
我们采用计划-执行-研究-行动(Plan-Do-Study-Act)方法成立了药剂科团队,并实施了多维药物干预。干预措施包括制定标准程序、指南和规定,借助信息系统(包括自动发药柜和前瞻性处方审核系统),提供沟通反馈(通过微信群),以及对麻醉科工作人员进行教育。干预措施从 2023 年 4 月至 9 月进行,重点是优化药物管理,节约成本,并提高麻醉团队成员的满意度,在 2023 年 10 月至 12 月进行了额外的观察。
干预措施后,药物管理实践得到改善。这些改进包括提高了记账程序的合规性,更严格地登记管制药物,以及更有效地处理液体残留。没有与高危药物或类似药物使用错误相关的不良事件。自动发药柜和前瞻性处方审核系统的引入显著提高了工作效率。微信群的使用促进了对不合理处方和药物相关问题的有效沟通。在干预前后接受手术的 29061 名患者中,药物比例和人均药物成本均显著降低(P=0.03,P=0.014)。人均药物成本从 723.43 元降至 572.78 元,降幅为 20.82%,在 9 个月的观察期内持续低于 600 元。地佐辛、布托啡诺、尖吻蝮蛇血凝酶、盐酸戊乙奎醚和乌司他丁等监测药物的人均成本显著降低(P<0.05)。此外,在收回的满意度问卷中,麻醉科工作人员的满意度高达 94.44%,对全面药物干预表示非常满意。
质量改进项目取得了显著的积极成果,可为类似医疗保健环境提供值得借鉴和复制的模式。