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乳腺原发性神经内分泌癌合并乳腺鳞状细胞癌：1例病例报告及文献复习

Primary neuroendocrine carcinoma of the breast in association with squamous cell carcinoma of the breast: A case report and review of the literature.

作者信息

Younes Bencherifi, Zakaria Bousada, Doha Karoini, Mustapha Benhessou, Simohamed Ennachit, Mohamed El Karroumi

机构信息

Gynecology Department, Univesity Hospital Ibn Rochd, Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, Morocco.

Gynecology Department, Univesity Hospital Ibn Rochd, Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, Morocco.

出版信息

Int J Surg Case Rep. 2023 Oct;111:108813. doi: 10.1016/j.ijscr.2023.108813. Epub 2023 Sep 14.

DOI:10.1016/j.ijscr.2023.108813
PMID:37717367
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10514093/
Abstract

INTRODUCTION AND IMPORTANCE

Squamous cell carcinoma associated with primary neuroendocrine carcinoma (NEC) of the breast, also known as composite tumor, is an extremely rare malignancy with a very poor prognosis.

PRESENTATION OF CASE

We report the case of a patient treated in our department for primary neuroendocrine carcinoma of the breast associated with squamous cell carcinoma by radical surgery.

CLINICAL DISCUSSION

Diagnosis is based on histology and, above all, immunohistochemistry. Management depends on the primary or secondary origin of the neuroendocrine component, which constitutes the prognostic element.

CONCLUSION

Squamous cell carcinoma associated with neuroendocrine carcinoma of the breast is an aggressive tumor. Due to its rarity, it is difficult to diagnose and to determine the most appropriate therapeutic protocol.

摘要

引言与重要性

乳腺原发性神经内分泌癌（NEC）相关的鳞状细胞癌，也称为复合性肿瘤，是一种极其罕见的恶性肿瘤，预后极差。

病例介绍

我们报告了一例在我院接受根治性手术治疗的乳腺原发性神经内分泌癌合并鳞状细胞癌患者的病例。

临床讨论

诊断基于组织学，尤其是免疫组织化学。治疗取决于神经内分泌成分的原发或继发来源，这是预后的决定因素。

结论

乳腺神经内分泌癌相关的鳞状细胞癌是一种侵袭性肿瘤。由于其罕见性，难以诊断并确定最合适的治疗方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbbe/10514093/95d1424f9c02/gr10.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbbe/10514093/ef0ff39d6741/gr4.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbbe/10514093/e6226dfb3228/gr6.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbbe/10514093/64c79429dda1/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbbe/10514093/2d223e0469e2/gr9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbbe/10514093/95d1424f9c02/gr10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbbe/10514093/2db72ee98a98/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbbe/10514093/15437d770e14/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbbe/10514093/1fb9c2bd5468/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbbe/10514093/ef0ff39d6741/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbbe/10514093/c86722b0bdaf/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbbe/10514093/e6226dfb3228/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbbe/10514093/e75cbd795ece/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbbe/10514093/64c79429dda1/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbbe/10514093/2d223e0469e2/gr9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbbe/10514093/95d1424f9c02/gr10.jpg

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