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高压氧治疗儿童:329 例经验。

Hyperbaric oxygen treatment in children: experience in 329 patients.

机构信息

Department of Hyperbaric Medicine, University of Health Sciences, Izmir Bozyaka Training and Research Hospital, Izmir, Turkey.

Corresponding author: Dr Figen Aydin, Saim Çıkrıkçı Cad. No:59, 35110 Karabağlar/İzmir, Turkey,

出版信息

Diving Hyperb Med. 2023 Sep 30;53(3):203-209. doi: 10.28920/dhm53.3.203-209.

DOI:10.28920/dhm53.3.203-209
PMID:37718293
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10735713/
Abstract

INTRODUCTION

Paediatric patients, like adults, may undergo hyperbaric oxygen treatment (HBOT) in both life-threatening situations and chronic diseases. There are particular challenges associated with managing paediatric patients for HBOT. This paper documents the indications, results, complications, and difficulties that occur during HBOT for a large cohort of paediatric patients and compares them with adult data in the literature. Methods used to reduce these difficulties and complications in children are also discussed.

METHODS

This was a 15-year retrospective review of paediatric patients treated with HBOT at two hyperbaric centres. Between January 2006 and June 2021, patients under the age of 18 who received at least one session of HBOT were included.

RESULTS

Three hundred and twenty-nine paediatric patients underwent a total of 3,164 HBOT exposures. Two-hundred and fifty-four patients (77.2%) completed treatment as planned and 218 (66.5%) achieved treatment goals without complications. Two patients treated for carbon monoxide poisoning exhibited neurological sequelae. Amputation was performed in one patient with limb ischaemia. Middle ear barotrauma events occurred in five treatments. No central nervous system oxygen toxicity was recorded during the treatments.

CONCLUSIONS

This patient series indicates that HBOT can be safely performed in pediatric patients with low complication rates by taking appropriate precautions. The cooperation of hyperbaric medicine physicians and other physicians related to paediatric healthcare is important in order for more patients to benefit from this treatment. When managing intubated patients an anaesthesiologist may need to participate in the treatment in order to perform necessary interventions.

摘要

简介

儿科患者与成人一样,可能会在危及生命的情况下和慢性病中接受高压氧治疗(HBOT)。管理儿科患者进行 HBOT 存在特殊挑战。本文记录了大量儿科患者接受 HBOT 的适应证、结果、并发症和治疗过程中遇到的困难,并与文献中的成人数据进行了比较。还讨论了用于减少这些儿科患者困难和并发症的方法。

方法

这是对两家高压氧中心接受 HBOT 治疗的 15 名儿科患者进行的回顾性研究。2006 年 1 月至 2021 年 6 月期间,纳入至少接受过一次 HBOT 的年龄在 18 岁以下的患者。

结果

329 名儿科患者共接受了 3164 次 HBOT 暴露。254 名患者(77.2%)按计划完成了治疗,218 名患者(66.5%)在无并发症的情况下达到了治疗目标。两名接受一氧化碳中毒治疗的患者出现了神经后遗症。一名肢体缺血患者进行了截肢。五例中耳气压伤发生。在治疗过程中未记录到中枢神经系统氧毒性。

结论

本患者系列表明,通过采取适当的预防措施,HBOT 可安全用于儿科患者,并发症发生率低。高压医学医生和与儿科保健相关的其他医生的合作对于使更多患者受益于这种治疗非常重要。在管理插管患者时,麻醉师可能需要参与治疗以进行必要的干预。

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Hyperbaric Oxygen for Lower Limb Trauma (HOLLT): an international multi-centre randomised clinical trial.高压氧治疗下肢创伤(HOLLT):一项国际多中心随机临床试验。
Diving Hyperb Med. 2022 Sep 30;52(3):164-174. doi: 10.28920/dhm52.3.164-174.
2
The Effects of Hyperbaric Oxygenation on Oxidative Stress, Inflammation and Angiogenesis.高压氧对氧化应激、炎症和血管生成的影响。
Biomolecules. 2021 Aug 14;11(8):1210. doi: 10.3390/biom11081210.
3
The myopic shift associated with hyperbaric oxygen administration is reduced when using a mask delivery system compared to a hood - a randomised controlled trial.与面罩输送系统相比,使用头罩进行高压氧治疗时,近视偏移会减少——一项随机对照试验。
Diving Hyperb Med. 2019 Dec 20;49(4):245-252. doi: 10.28920/dhm49.4.245-252.
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Seizure frequency in more than 180,000 treatment sessions with hyperbaric oxygen therapy - a single centre 20-year analysis.超过180,000次高压氧治疗疗程中的癫痫发作频率——单中心20年分析
Diving Hyperb Med. 2019 Sep 30;49(3):167-174. doi: 10.28920/dhm49.3.167-174.
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Hyperbaric oxygenation in pediatrics: indications in the light of evidence - based medicine.儿科高压氧治疗:基于循证医学的适应症
Dev Period Med. 2019;23(2):142-148. doi: 10.34763/devperiodmed.20192302.142148.
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Middle ear barotrauma during hyperbaric oxygen therapy; a review of occurrences in 5,962 patients.高压氧治疗期间的中耳气压伤;对5962例患者发病情况的综述
Undersea Hyperb Med. 2019;46(2):101-106.
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