Department of Anaesthesiology, Ziauddin University, Clifton, Karachi, Sindh, 75000, Pakistan.
Department of Surgery, Radboud University Medical Center, 6525 GA, Nijmegen, The Netherlands.
Pain Manag. 2023 Sep;13(9):555-567. doi: 10.2217/pmt-2023-0033. Epub 2023 Sep 18.
To study the efficacy of quadratus lumborum block (QLB) and transversus abdominis plane (TAP) in laparoscopic nephrectomy patients. We conducted a meta-analysis of randomized controlled trials for QLB and/or TAP technique compared with each other or a control. Direct analysis of 24 h post-op pain score at rest for each compared with control showed significant reduction, QLB (mean differences [MD] [95% CI]: -1.12 [-1.87,-0.36]; p = 0.004) and TAP (MD [95% CI]: -0.36 [-0.59, -0.12]; p = 0.003). With movement both were respectively lower than control QLB (MD [95% CI]: -1.12 [-1.51, -0.72]; p = <0.0001) and TAP (MD [95% CI]: -0.50 [-0.95, -0.05]; p = 0.03). Moreover, QLB demonstrated less risk 24 h of post-op nausea vomiting (PONV) versus control (PONV; risk ratios [RR] [95% CI]: 0.64 [0.45,0.90]; p = 0.01). TAP and QLB reduce pain scores compared with control, whereas only QLB reduces PONV compared with control.
研究竖脊肌平面阻滞(QLB)和腹横肌平面阻滞(TAP)在腹腔镜肾切除术中的疗效。我们对 QLB 和/或 TAP 技术与其他技术或对照组进行了随机对照试验的荟萃分析。直接分析每个与对照组相比的 24 小时术后静息时疼痛评分,结果显示明显降低,QLB(平均差异 [MD] [95%CI]:-1.12 [-1.87,-0.36];p = 0.004)和 TAP(MD [95%CI]:-0.36 [-0.59,-0.12];p = 0.003)。活动时,两者均低于对照组 QLB(MD [95%CI]:-1.12 [-1.51,-0.72];p <0.0001)和 TAP(MD [95%CI]:-0.50 [-0.95,-0.05];p = 0.03)。此外,QLB 与对照组相比,术后 24 小时恶心呕吐(PONV)的风险更低(PONV;风险比 [RR] [95%CI]:0.64 [0.45,0.90];p = 0.01)。与对照组相比,QLB 和 TAP 均能降低疼痛评分,而只有 QLB 能降低 PONV 与对照组相比。