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孕期粪类圆线虫高度感染综合征

Strongyloides stercoralis Hyperinfection Syndrome in Pregnancy.

作者信息

Akers Allison N, Vest Adriana, Schenone Claudio V, Rodriguez Alejandro

机构信息

Obstetrics and Gynecology, University of South Florida, Tampa, USA.

出版信息

Cureus. 2023 Aug 16;15(8):e43568. doi: 10.7759/cureus.43568. eCollection 2023 Aug.

Abstract

Strongyloidiasis is a parasitic infection with a high global burden of disease. Hyperinfection syndrome is a life-threatening complication that predominantly affects immunosuppressed individuals, such as those receiving corticosteroid treatment. Despite its worldwide prevalence, little is known about the clinical effects of this condition on the feto-maternal dyad during pregnancy. We present a case of placental abruption leading to preterm delivery in a pregnancy complicated by  hyperinfection syndrome following antenatal corticosteroid use. Although rare, this condition is associated with high mortality rates and adverse pregnancy outcomes. Therefore, screening at-risk individuals may be warranted in pregnancies where antenatal corticosteroid administration is considered.

摘要

类圆线虫病是一种全球疾病负担较高的寄生虫感染。高度感染综合征是一种危及生命的并发症,主要影响免疫功能低下的个体,如接受皮质类固醇治疗的患者。尽管该病在全球范围内普遍存在,但对于孕期母婴二元组中这种情况的临床影响知之甚少。我们报告一例因产前使用皮质类固醇后并发高度感染综合征导致胎盘早剥并早产的病例。虽然罕见,但这种情况与高死亡率和不良妊娠结局相关。因此,在考虑进行产前皮质类固醇给药的妊娠中,对高危个体进行筛查可能是必要的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38ce/10503402/af8e932db2b2/cureus-0015-00000043568-i01.jpg

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